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Volume 9 International Journal of Advancements in Technology
ISSN: 0976-4860 3D Printing 2018
March 19-20, 2018
March 19-20, 2018 | London, UK
2nd International Conference on
3D Printing Technology and Innovations
3D printed cellulose nanocrystals based hydrogel scaffolds for biomedical applications
Sahar Sultan and Aji P Mathew
Stockholm University, Sweden
C ellulose nanoparticles extracted from natural resources are used extensively in biomedical field because of its favorable
biological properties, such as, biocompatibility, biodegradability and low toxicity. However, the 3D printing of these
nanoparticles have opened a new area of customization, personalization with better control over structural properties. Much
work is devoted to cellulose nanofibers (CNFs) and its biomedical products are already commercialized. Recently the 3D
printing of cellulose nanocrystals (CNCs) and the directionality induced in the 3D constructs due to shear-induced orientation
of CNCs have open challenges for CNCs to get as much attention as CNFs in biomedical field. Therefore, CNCs based double
crosslinked interpenetrating polymer network (IPN) hydrogel has been made and 3D printed into scaffolds with and without
gradient porosity. The pore sizes are in the range of 80-2080 µm and 195-2382 µm in the wet and freeze-dried states respectively.
The directionality studies showed that degree of orientation varies between 61-76 % depending on the point of measurement
within the 3D construct. The nanoscaled roughness (visible for scanning electron images) and mechanical properties (in
aqueous medium) are favorable for cell interaction. We believe that we have opened the route for CNCs to enter into the
biomedical field. The interesting part of this study is that with a little optimization of pore size and ink composition, our 3D
printed scaffolds will have potential applications in bone and/or cartilage regeneration.
Recent Publications
1. Sultan S, SiqueiraG, ZimmermannT,MathewAP (2017) 3Dprinting of nano-cellulosic biomaterials formedical applications.
Current Opinion in Biomedical Engineering. 2:29-34.
2. Markstedt K, Mantas A, Tournier I, Martínez Ávila H, Hägg D, Gatenholm P (2015) 3D bioprinting human chondrocytes
with nanocellulose–alginate bioink for cartilage tissue engineering applications. Biomacromolecules. 16(5):1489-1496.
3. Siqueira G, Kokkinis D, Libanori R et al. (2017) Cellulose nanocrystal inks for 3D printing of textured cellular architectures.
Advanced Functional Materials. 27(12): 1604619.
Biography
Sahar Sultan is a second year PhD student in Stockholm University, Sweden. She is actively working with 3D printing of cellulose nanoparticles. She has also
served the industry for 5 years by working as a researcher and Safety Officre in a solar cell company called Exeger, Sweden AB, Stockholm, Sweden. She is
interested in researching 3D printing and cellulose nanoparticles.
Sahar Sultan et al., Int J Adv Technol 2018, Volume 9
DOI: 10.4172/0976-4860-C1-002