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Volume 5 Journal of Pharmaceutical Care & Health Systems Asia Pharma 2018
July 18-20, 2018
Page 14
Notes:
conferenceseries.com
July 18-20, 2018 Melbourne, Australia
15th Asia-Pacific Pharma Congress
Turbinaria ornata- Amarine algal drug treasure
For the past few decades, compounds from marine algae have been gaining importance due to the vast chemical diversity.
In our continuous research on algae, scientific data and traditional claims prompted us to investigate on the brown alga
Turbinaria ornata (Family: Sargassaceae). The cyclohexane, ethyl acetate and methanolic extracts of Turbinaria ornata were
subjected to wide pharmacological screening. Among the extracts, cyclohexane exhibited cholinomimetic activity by inhibiting
the cholinesterase significantly at P<0.01 in the presence of acetyl choline, ethyl acetate extract possessed antifungal activity
with the MIC of 500 mcg/mL concentration and methanolic extract showed the highest in vitro DPPH free radical scavenging
activity (70.78%) which was comparable to ascorbic acid, a positive control (78.16%). Also, it showed significant anti-diabetic
activity against streptozotocin and anti-obesity activity against Atorvastatin (P<0.001). So, it is very clear that the brown alga has
beneficial effects on oxidative stress, microbes, blood glucose levels, cholesterol level, HDL, LDL, body weight due to presence
of its chemical constituents like gallic acid, quercetin, oxygenated steroids and glycosides which were identified by various
parameters. Thus, Turbinaria ornata proved to be a rich source of potential compounds for further research.
Biography
Sadish Kumar Shanmugam is the Director of I T S College of Pharmacy, Ghaziabad, India. He has been working as a Professor since 2010. He has over 2 decades
of research and teaching experience. He is a Member of various professional bodies including Royal Society of Chemistry, UK. He has published 2 books, 30
research articles and presented research papers at conferences held in South Korea, USA, Germany and Egypt and guided over 30 MPharm research projects in
Marine and other natural products, guiding PhD projects as well.
Sadish Kumar Shanmugam
I T S College of Pharmacy, India
Sadish Kumar Shanmugam, J Pharma Care Health Sys 2018, Volume 5
DOI: 10.4172/2376-0419-C1-025