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Volume 5
Journal of Pharmaceutical Care & Health Systems
Asia Pharma 2018
July 18-20, 2018
Page 23
Notes:
conference
series
.com
July 18-20, 2018 Melbourne, Australia
15
th
Asia-Pacific Pharma Congress
Bioactive compounds from
Gelidiella acerosa
, a red alga
Algal resources have a tremendous potential to be explored for the benefits of the mankind.
Gelidiella acerosa
is a genus of
Red algae (Family: Gelidiellaceae) with high economic value found in many parts of India. As
Gelidiella acerosa
is used in the
production of high quality agar, reported to possess a variety of phytoconstituents including Flavonoids, Alkaloids, Tannins,
Proteins, Sulfated polysaccharides, Sulfono glycolipid, Sesquiterpenes, Monoterpenes, Phenols and various pharmacological
activities, prompted us to investigate on this red alga with its hexane, ethyl acetate and methanolic extracts.
Among the extracts, methanolic extract of
Gelidiella acerosa
exhibited the highest percentage of free radical scavenging activity
(68.42%) by Invitro DPPH assay which was comparable to that of the standard Ascorbic acid (76.55%). Methanolic extract also
possessed the highest anti-inflammatory potential followed by ethyl acetate and hexane extracts in the Carrageenan induced paw
edema and Cotton pellet induced granuloma models and it was found to be significant at p<0.001. The percentage inhibition was
found to be 64.60% when compared to the standard, Diclofenac sodium (70.45%) at 10mg/kg concentration.
The antioxidant and anti-inflammatory activity of methanolic extract could be attributed to the highest amount of Flavonoid
and Phenolic content, which were estimated to be 48.5 mg/g Quercetin and 34.34 mg/g Gallic acid equivalent respectively.
Further investigations should be carried out to discover other potential phytoconstituents and pharmacological activities of
G.
acerosa
.
Biography
Sadish Kumar Shanmugam is the Director of I T S College of Pharmacy, Ghaziabad, India. He has been working as a Professor since 2010. He has over 2 decades
of research and teaching experience. He is a Member of various professional bodies including Royal Society of Chemistry, UK. He has published 2 books, 30
research articles and presented research papers at conferences held in South Korea, USA, Germany and Egypt and guided over 30 MPharm research projects in
Marine and other natural products, guiding PhD projects as well.
dir.pharm@its.edu.inSadish Kumar Shanmugam
I T S College of Pharmacy, India
Sadish Kumar Shanmugam, J Pharma Care Health Sys 2018, Volume 5
DOI: 10.4172/2376-0419-C1-025