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Volume 9

Journal of Nutrition & Food Sciences

ISSN: 2155-9600

Clinical Nutrition 2019

March 04-06, 2019

March 04-06, 2019 | Barcelona, Spain

24

th

International Conference on

Clinical Nutrition

Effect of different levels of oral bovine lactoferrin from iron-fortified formula on iron metabolism of

anemic infants

Ke Chen

Chongqing Medical University, China

Objective

: To evaluate the effect of iron-fortified formula with different concentrations of bovine lactoferrin (bLF)

on improvement of the anemic status in term infants who previously breast-fed.

Method

: In this prospective multi-center controlled intervention study, a total of 108 infants aged 6-9 months who

previously breast-fed but weaned were selected. All subjects were divided into three groups with the sequence of

outpatient: fortified group 1 (FG1) with a bLF concentration of 38 mg/100 g, FG2 with 76 mg/100 g, FG0 with

free of bLF. The intervention duration were 3 months. The levels of weight, height and head circumference and the

concentration of Hemoglobin (Hb), Serum Ferritin (SF), serum Transferring Receptor (sTfR) were measured and

sTfR-SF index (TFR-F index) and Total Body Iron Content (TBIC) were computed before and after intervention,

respectively.

Result

: The primary outcome measures were obtained from 96 infants (35, 33 and 28 for FG0, FG1 and FG2,

respectively). After one month intervention, the changes of Hb level showed no statistical difference [(113.18±10.2),

(109.78±8.3) vs. (111.83±8.6) g/L, for FG0, FG1 and FG2, respectively] among the three groups, however, the Hb level

of infants in FG2 were significantly higher than those of infant in the other two groups after 3 months intervention

[(116.49±8.0), (116.58±6.4) vs. (121.50±5.1) g/L, for FG0, FG1 and FG2, respectively] (p<0.05).

Conclusion

: The present data indicated that the formula fortified with bLF by 76 mg/100 g formula positively and

additionally affected the Hb of anemic infants who previously breastfed when compared with bLF fortified by 38

mg/100 g formula and formula without bLF.

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J Nutr Food Sci 2019, Volume 9

DOI: 10.4172/2155-9600-C2-093