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June 19-20, 2017 Philadelphia, USA

14

th

International Conference on

Clinical and Experimental Dermatology

Volume 8, Issue 4 (Suppl)

J Clin Exp Dermatol Res, an open access journal

ISSN:2155-9554

Dermatology 2017

June 19-20, 2017

Terahertz multispectral reconstructive imaging of biological specimen

Anis Rahman

1

, Babar Rao

2

and

Aunik Rahman

1

1

Rutgers University, USA

2

Applied Research & Photonics, USA

T

erahertz multispectral reconstructive imaging is an effective tool for soft tissue imaging without any radiation damage

kike X-ray. Here, examples of biological tissue imaging are outlined to elucidate the technique. Reconstructive imaging

utilizes the technique of rasterizing a specimen over a given area. ARP’s instrument allows the T-ray beam to be focused on

a given layer under the surface; therefore, a 3D volume may be rasterized on a layer by layer basis. The reflected intensity is

recorded preserving the exact coordinates over which measurements are done. The intensity matrix is then converted to image

via inverse gridding algorithm. The algorithm is capable of accurate representation of the measured object similar to a charged

couple device as has been explained previously. Here we present images of human skin under different diseased conditions as

compared with healthy skin samples. Fig. 1(a) exhibits terahertz reconstructive images of a healthy skin sample where regular

cellular pattern is visible. This is expected from the healthy skin tissue. Fig. 1(b) shows an image of a skin sample diagnosed

for basal cell carcinoma. As evident from Fig. 1(b), diseased skin sample has lost its regular cellular pattern which is present

for the healthy skin sample. This lack of systematic cellular structure may serve as an easy visual means to indicate that there

is something wrong with the sample. As outlined in reference [1], a combination of presence or absence of regular cellular

structure, terahertz spectral comparison, and lack or presence or layering information is expected to serve as a fool proof

diagnostic tool for different kind of skin cancers.

Figure 1: (a): terahertz image of healthy skin tissue. (b): Image of skin tissue diagnosed for basal cell carcinoma showing distorted cell structure

Biography

Anis Rahman is an acclaimed Scientist in the field of Nanotechnology. He is a winner of many scientific awards including NASA Nanotech Brief’s “Nano-50” award

twice; CLEO/Laser Focus World’s “Innovation award”. He is the Founder of a terahertz company in Harrisburg, Pennsylvania. He is a recognized Scientific Leader

and Member of professional organizations including the American Chemical Society (ACS), The Optical Society of America (senior member), and the SPIE. He is

the current Chair of Small Chemical Businesses Division of the ACS. He has been an author and co-author of more than 120 papers in peer reviewed journals and

conference proceedings.

[email protected]

Anis Rahman et al., J Clin Exp Dermatol Res 2017, 8:4 (Suppl)

DOI: 10.4172/2155-9554-C1-059