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Volume 6

Journal of Oral Hygiene & Health

Endodontics & Orthodontics 2018

August 17-18, 2018

AUGUST 17-18, 2018 TOKYO, JAPAN

ANNUAL CONGRESS ON

Endodontics, Orthodontics,

Prosthodontics and Dental Implants

Samaneh Keshavarz, J Oral Hyg Health 2018, Volume 6

DOI: 10.4172/2332-0702-C1-008

Comparison of 0.2% chlorhexidine gel and 10% betadine on healing of tooth socket in mice

Samaneh Keshavarz

Rafsanjan University of Medical Sciences, Iran

Statement of the Problem:

Tooth extraction is the most common surgical procedure performed in dental office. Various

drugs are used to accelerate wound healing in soft and bone tissues. In this study, the effect of 0.2% chlorhexidine gel and 10%

betadine gel on tooth socket healing was investigated.

Materials & Method:

This experimental study was performed on 45 male mice randomly divided into three groups of 15.

Under general anesthesia, the right maxillary second molar of all the mice were extracted. The socket of the first group was

covered with 0.2% chlorhexidine gel and the second group was covered with 10% betadine gel and the socket of third group

was left empty. On the third, seventh and fourteenth days after surgery, one third of the animals were sacrificed from each

group. Then the prepared slides from each group were examined.

Result:

The extent of granulation tissue on the third day after tooth extraction in the chlorhexidine group was greater than

the remaining two groups. The number of lymphocytes on the seventh day after tooth extraction in the chlorhexidine group

was lower than the control group. The number of macrophage on the 14

th

day after tooth extraction in the chlorhexidine and

betadine groups was lower than the control group. The numbers of fibroblasts in the chlorhexidine group on the fourteenth day

after tooth extraction was higher than the control group. These differences were statistically significant.

Conclusion & Significance:

According to the results of this study, 0.2% chlorhexidine gel can accelerate the process of tooth

socket healing.

Biography

Samaneh Keshavarz has completed her PhD from Shahid Sadoughi University of Medical Sciences, Iran. She has published about 6 papers in reputed journals

and has published 2 books.

s.keshavarz@rums.ac.ir