endodontics-orthodontics-2018-tracks

9 / 16

Page 27
conferenceseries.com
Volume 6 Journal of Oral Hygiene & Health Endodontics & Orthodontics 2018
August 17-18, 2018
AUGUST 17-18, 2018 TOKYO, JAPAN
ANNUAL CONGRESS ON
Endodontics, Orthodontics,
Prosthodontics and Dental Implants
08 09
Qiaojie Luo et al., J Oral Hyg Health 2018, Volume 6
DOI: 10.4172/2161-0673-C1-014
Establishment of a topography analytical method for activity prediction of nano-submicro-micro
hybrid titanium surfaces
Qiaojie Luo, Weiwei Lao and Xiaodong Li
Zhejiang University, China
Dential implants of micro topographical surfaces have been widely used in clinic and has obtained high success
rate, through the mechanism of increasing the local factor levels to produce an osteogenic environment. Nowadays,
nontopographical features are hoped to improve osteointegration and surfaces of Nano-Submicro-micro hybrid topography
are prized in biomaterial research. However, to obtain the Nano-Submicro-micro hybrid topographical implant of desirable
property is hit-and-miss, without guidance or quantitative topographical parameters to predict biological performance. In
the present study, we constructed a series of titanium surfaces of Nano-Submicro-micro topographical feature, through the
combination of sandblasting, acid etching and alkali treatment. With the increase time in alkali treatment, the Nano-scale
structure strengthened with the micro and Submicro scale structures weakened. In vitro and in vivo studies showed that the
osteogenesis of these surfaces, increased first and then decreased. We constructed a set of SEM-image dependent topography
analytical methods to quantitatively analyze the topography features of each scales. Based on the series titanium surfaces with
high consistence in surface chemistry, matter phase structures and the topography analytical methods, we found that the
complexity of structure in each scale played important role in biological activity and it was the sum of complexity in all scales
that determined the overall performance of the implant. In further study, we will analyze more surfaces to refine the analysis
method and would be a promising model to predict the surfaces of the highest bioactivity in a specific topographical series of
implant surfaces.
Biography
Qiaojie Luo has completed her PhD degree from Zhejiang University and her Postdoctoral research in 2017. Currently, she is focusing on the surface modification
of dental implants and osseointegration mechanism of titanium.