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.com
Volume 6, Issue 9 (Suppl)
Dentistry 2016
ISSN: 2161-1122 Dentistry, an open access journal
Euro Dental Congress 2016
October 24-26, 2016
October 24-26, 2016 Rome, Italy
15
th
Euro Congress on
Dental & Oral Health
Vita Zalite et al., Dentistry 2016, 6:9 (Suppl)
http://dx.doi.org/10.4172/2161-1122.C1.006The design of calcium phosphate particle for tooth hard tissue remineralization
Vita Zalite, Janis Locs
and
Jana Vecstaudza
Riga Technical University, Latvia
D
ental caries is a world-wide oral disease. At the initial stage of caries lesions, cariogenic bacteria attack tooth enamel, leading to
demineralized areas on the tooth surface. Therefore, the investigation includes the design of calcium phosphate (CaP) particles
with caries preventive effect due to bioavailable calcium and tailored particle morphology. The aim is to obtain CaP particles with
properties close to enamel crystals (20-100 nm) and dentine tubules (2-4 µm). CaO and H
3
PO
4
were used as precursors to synthesize
CaP. The Ca/P ratio of products was chosen under 1.67 to obtain calcium deficient hydroxyapatite. One part of the product was spray-
dried (spCaP) and remaining part- left as paste (pCaP). The evaluation of products composition by X-ray diffraction (XRD) and
fourier transform infrared spectrometry (FTIR) was done. Morphology was investigated by scanning electron microscopy (SEM).
FTIR showed a characteristic vibrations of functional groups of apatite. XRD patterns confirmed apatite phase with low crystallinity.
The Ca/P ratio was in the range from 1.64 to 1.60. SEM micrographs showed nanorods (length 50-200 nm, diameter 25-60 nm) for
pCaP and spherical agglomerates (1-10 µm) for spCaP samples. The obtained CaP are chemically very similar to dental hard tissues.
In addition, the morphology of pCaP particles is compatible with enamel crystals while size of spCaP agglomerates fits well with the
dimensions of dentine tubules. The combination of pCaP and spCaP have a potential to decrease a risk of caries development and this
hypothesis will be tested during
in vitro
studies.
Biography
Vita Zalite has completed his PhD in Material Science at Riga Technical University (RTU). He is a Researcher at Rudolfs Cimdins Riga Biomaterials and
Development Centre (RC RBIAC).
vita.zalite@rtu.lv