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Volume 9
Journal of Health & Medical Informatics
ISSN: 2157-7420
Medical Informatics 2018
July 05-06, 2018
July 05-06, 2018 | Berlin, Germany
6
th
International Conference on
Medical Informatics & Telemedicine
RESTORATION OF INSULIN PRODUCTION AND PROTECTIVE ACTION AGAINST
DIABETES COMPLICATIONS BYWAKOUBAAN EXTRACT OF LOCAL PLANT
Felix Kouame
a
a
University of Port Harcourt, Nigeria
Statement of the Problem:
Globally, an estimated 422 million adults were living with diabetes in 2014, compared to 108
million in 1980. Diabetes and obesity have reached such proportions worldwide we’re talking about pandemic. Diabetes and
its complications bring about substantial economic loss to people with diabetes and their families and to health systems and
national economies through direct medical costs and loss of work and wages. The purpose of this study is to evaluate the
restoration of insulin production by Wakouba in diabetic rats and evaluate the protective action against diabetes complications.
Methodology & Theoretical Orientation:
We focused first on evaluating in diabetics rats treated by Wakouba, the rate of
glucose and the level of insulin. Histopathological sections of the pancreas were observed. And secondly, we evaluated the
evolution of NO production and the activity of catalase to see the action of Wakouba during the diabetes in these rats.
Findings:
The results show, blood glucose decreases and normalizes and the production of insulin increases during the
treatment of the diabetic animals by Wakouba. At the same time, Wakouba restores the integrity of the beta Langerhans cells.
The treatment by Wakouba restores NO production which will play fully its physiological role in the nervous, cardiovascular,
genitourinary and digestive and immune systems in diabetic rats.
Conclusion & Significance:
Wakouba restores the integrity of the beta cells of Langerhans, by converting pancreatic α cells
into pancreatic β cells. We can also say that Wakouba participates to the restoration of the nervous, cardio-vascular, genito-
urinary, and digestive and immune systems, in the organism of these diabetic rats. Wakouba may be also involved in the fight
against insulin resistance.
Biography
Kouame Felix is a PhD student in Biotechnology and Pharmacology of Natural Substances in the Laboratory of Pharmacodynamie Biochimique of Universite Felix
Houphouet Boigny de Cocody Abidjan. He is working to find new medical molecular against diseases from natural substances. He is having a Bachelors degree in
Biochemistry and Microbiology and Master’s degree in Biotechnology and Pharmacology of Natural Substances. He also has a Master’s degree in Business administration
in Abidjan and a certificate in Marketing and Commercial Engineering. He is working for more than 14 years in Sales, Marketing, International Trades, Shipping and
Logistics. He is currently working for an international agribusiness, as a commercial representative in charge of shipping and logistics.
broufelixk@yahoo.frKouame Felix et al., J Health Med Informat 2018, Volume 9
DOI: 10.4172/2157-7420-C1-021