nutrition-and-health-2017_posters-accepted-abstracts

17 / 24

Page 69
conferenceseries.com
February 20-21, 2017 Berlin, Germany
9th International Congress on
Nutrition & Health
Volume 7 Issue 1 (Suppl) J Nutr Food Sci
ISSN:2155-9600 JNFS, an open access journal Nutrition & Health 2017
February 20-21, 2017 Berlin, Germany
Organic chromium forms modifies the expression of orexin and its related receptors and glucose
transporters in heat stressed hens
Oguzhan Ozdemir, Mehmet Tuzcu, Nurhan Sahin, Cemal Orhan, Zeynep Tuzcu and Kazim Sahin
Firat University, Turkey
High ambient temperature reduces the metabolic rates and alters post-absorptive metabolism, regardless of the decreased
feed intake. Recent studies reported that orexins/hypocretins regulate energy intake and expenditure, glucose and lipid
metabolism by modulating hepatic gluconeogenesis, leading to generation of the blood glucose oscillation. We previously found
that organic chromium forms reduces environmental stress factors, regulates glucose metabolism in poultry reared under high
ambient temperature. However, the regulation of orexin system by heat stress and Cr supplementation itself remains unclear. Here,
we investigated the effects of heat stress and organic chromium forms on the hepatic expression of orexin (ORX) and its related
receptors (ORXR1/2) and glucose transporters (GLUTs) in laying hens. The expression of ovary GLUTs was also studied. We found
that heat stress significantly down-regulated ORX, ORXR1/2 and GLUT-2 in the liver and GLUT-1 and GLUT-4 in the ovary cells of
laying hens. However, chromium form (CrPic and CrHis) supplementation increased hepatic ORX, ORXR1/2 and GLUT-2and ovary
GLUT-1 and GLUT-4 in laying hens (P<0.05). In conclusion, the present data indicated that hepatic orexin system and GLUTs could
be a molecular signature in the heat stress response, and CrPic and CrHis supplementation may alleviate negative effects of heat stress
by regulation of orexin system and glucose transporters.
J Nutr Food Sci 2017, 7:1 (Suppl)