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Volume 6, Issue 9(Suppl)

J Obes Weight Loss Ther 2016

ISSN: 2165-7904 JOWT, an open access journal

Page 52

Obesity 2016

December 08-10, 2016

conferenceseries

.com

Obesity & Weight Management

December 08-10, 2016 Dallas, USA

10

th

International Conference and Exhibition on

J Obes Weight Loss Ther 2016, 6:9(Suppl)

http://dx.doi.org/10.4172/2165-7904.C1.043

Effects of oral and subcutaneous administration of Roselle calyx (

H. sabdariffa

) extract on weight

management and controls

Odigie Bolaji Efosa

University of Benin, Nigeria

R

oselle (

Hibiscus sabdariffa

L., family Malvaceae) is consumed in Nigeria as a refreshing drink and for therapeutic purposes. This

study was to examine the effects of

H. sabdariffa

calyx extract on the body and organ weight of Albino rats. The second goal was

to compare the effects on the target organs via routes of administration (oral against subcutaneous). Sixty Albino rats of both sexes

with an average weight of 204.14±2.1g (Mean±S.E.M) were assigned by sex, age and weight to a control group (VA and VB) and

test groups (IA to IVA and IB to IVB). Empirical measurements on body weight was conducted prior to and after the experiment.

They were administered with varying concentrations of the extract by oral and subcutaneous routes (10 to 50 mg/kg) for 30 days

at 2 days interval. On day 31, all rats were sacrificed by anaesthetization. The internal organs were excised, weighed, grossed and

fixed in Bouin’s solution for 48 hrs prior to histological processing. Sections were obtained at 3-5 microns and stained with Mayer’s

haematoxylin and eosin for light microscopy. No comparable changes are observed histologically. However, gross effects on the

organs and body weight of experimental animals showed significant reduction when compared to the control (VA and VB) and test

groups (IA to IVA and IB to IVB). In comparison, with the oral administration, empirical measurement showed a massive weight loss

in the high dose treated animals (both routes of administration) but are marked in the oral route. Therefore, this study suggests that

H. sabdariffa

calyx extracts may be used for weight management and control. However, further studies are required to examine the

biochemical and hematological effects in Albino rats.

bolaji.odigie@uniben.edu

Do making habits or breaking habits influence weight loss and weight loss maintenance? A randomised

controlled trial

Gina Cleo

Bond University, Australia

Background:

Despite the significance placed on lifestyle interventions for obesity management, around 40% of weight loss is regained

over the first year following treatment, and much of the rest over the next three years. Two psychological concepts (habitual behaviour

and automaticity) have been suggested as the most plausible explanation of this overwhelming lack of long-term weight loss success.

Method:

We evaluated the efficacy of two interventions that explore these theories: Ten Top Tips (10TT) and Do Something Different

(DSD). 10TT promotes automaticity; this is the ability to perform tasks without awareness or deliberation. Therefore, diet and exercise

related behaviours become automatic or habitual. Conversely DSD promotes behavioural flexibility. This program disrupts daily

routines by assigning an individual with unstructured tasks to perform. Behavioural flexibility therefore has an inverse relationship

with automaticity and is defined as the measure of an individual’s range of mindful behaviours. Men and women (n=75), aged

51+6 (s.d.) years with body mass index 34.5+4.1 kg/m² were randomised to 12-week 10TT, DSD or no treatment control. Active

intervention participants underwent 12 weeks of the program with 12-months follow-up.

Results:

We collected data for weight, BMI, waist circumference as well as habitual behaviour and wellbeing. After 12 weeks

intervention, weight loss averaged 4.6 kg in the 10TT group, 4.1 kg in the DSD group and 1.3 kg in the control group. There was

significant improvement in wellbeing in the 10TT and DSD groups.

gcleo@bond.edu.au