

Volume 6, Issue 9(Suppl)
J Obes Weight Loss Ther 2016
ISSN: 2165-7904 JOWT, an open access journal
Page 52
Obesity 2016
December 08-10, 2016
conferenceseries
.com
Obesity & Weight Management
December 08-10, 2016 Dallas, USA
10
th
International Conference and Exhibition on
J Obes Weight Loss Ther 2016, 6:9(Suppl)
http://dx.doi.org/10.4172/2165-7904.C1.043Effects of oral and subcutaneous administration of Roselle calyx (
H. sabdariffa
) extract on weight
management and controls
Odigie Bolaji Efosa
University of Benin, Nigeria
R
oselle (
Hibiscus sabdariffa
L., family Malvaceae) is consumed in Nigeria as a refreshing drink and for therapeutic purposes. This
study was to examine the effects of
H. sabdariffa
calyx extract on the body and organ weight of Albino rats. The second goal was
to compare the effects on the target organs via routes of administration (oral against subcutaneous). Sixty Albino rats of both sexes
with an average weight of 204.14±2.1g (Mean±S.E.M) were assigned by sex, age and weight to a control group (VA and VB) and
test groups (IA to IVA and IB to IVB). Empirical measurements on body weight was conducted prior to and after the experiment.
They were administered with varying concentrations of the extract by oral and subcutaneous routes (10 to 50 mg/kg) for 30 days
at 2 days interval. On day 31, all rats were sacrificed by anaesthetization. The internal organs were excised, weighed, grossed and
fixed in Bouin’s solution for 48 hrs prior to histological processing. Sections were obtained at 3-5 microns and stained with Mayer’s
haematoxylin and eosin for light microscopy. No comparable changes are observed histologically. However, gross effects on the
organs and body weight of experimental animals showed significant reduction when compared to the control (VA and VB) and test
groups (IA to IVA and IB to IVB). In comparison, with the oral administration, empirical measurement showed a massive weight loss
in the high dose treated animals (both routes of administration) but are marked in the oral route. Therefore, this study suggests that
H. sabdariffa
calyx extracts may be used for weight management and control. However, further studies are required to examine the
biochemical and hematological effects in Albino rats.
bolaji.odigie@uniben.eduDo making habits or breaking habits influence weight loss and weight loss maintenance? A randomised
controlled trial
Gina Cleo
Bond University, Australia
Background:
Despite the significance placed on lifestyle interventions for obesity management, around 40% of weight loss is regained
over the first year following treatment, and much of the rest over the next three years. Two psychological concepts (habitual behaviour
and automaticity) have been suggested as the most plausible explanation of this overwhelming lack of long-term weight loss success.
Method:
We evaluated the efficacy of two interventions that explore these theories: Ten Top Tips (10TT) and Do Something Different
(DSD). 10TT promotes automaticity; this is the ability to perform tasks without awareness or deliberation. Therefore, diet and exercise
related behaviours become automatic or habitual. Conversely DSD promotes behavioural flexibility. This program disrupts daily
routines by assigning an individual with unstructured tasks to perform. Behavioural flexibility therefore has an inverse relationship
with automaticity and is defined as the measure of an individual’s range of mindful behaviours. Men and women (n=75), aged
51+6 (s.d.) years with body mass index 34.5+4.1 kg/m² were randomised to 12-week 10TT, DSD or no treatment control. Active
intervention participants underwent 12 weeks of the program with 12-months follow-up.
Results:
We collected data for weight, BMI, waist circumference as well as habitual behaviour and wellbeing. After 12 weeks
intervention, weight loss averaged 4.6 kg in the 10TT group, 4.1 kg in the DSD group and 1.3 kg in the control group. There was
significant improvement in wellbeing in the 10TT and DSD groups.
gcleo@bond.edu.au