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Volume 2, Issue 2 (Suppl)
Optom open access
ISSN: 2476-2075 OMOA, an open access journal
Ophthalmologists 2017
September 25-26, 2017
September 25-26, 2017 Dubai, UAE
11
th
Global
Ophthalmologists Annual Meeting
Sympathetic ophthalmia as a major sight-threatening disorder
Mohammed Alkhaibari
Saudi Arabia
S
O (sympathetic ophthalmia) is iris and eyeball inflammatory condition affecting both eyes that occurs after a penetrating
injuryas adelayedautoimmune reaction toeye injury. Patientspresentwithpain, photophobia, andparesisof accommodation,
metamorphopsia and mild to significant visual loss. The granulomatous anterior uveitis is accompanied by posterior segment
findings including moderate to severe vitritis, choroiditis, papillitis, perivasculitis, and yellow-white lesions of the retinal
pigment epithelium (Dalen-Fuchs nodules). The inflammation can lead to serious retinal detachment and macular edema.
Extraocular symptoms include headache, meningitis or cerebrospinal fluid pleocytosis, hearing loss, poliosis and vitiligo. The
inflammation is caused by a cell-mediated immune mechanism and autoimmune inflammatory response directed against
ocular self-antigens released after the initial injury. SO may occur after ocular trauma (47 to 65% of patients) or contusions.
Wounds involving the ciliary body are associated with the highest risk. Surgical interventions may also trigger SO, with
posterior segment surgery carrying a higher risk than anterior segment surgery. Diagnosis of SO is mainly based on patient
history and clinical presentation. Imaging studies (fluorescein or indocyanine green angiography, B-scan ultrasonography and
optical coherence tomography) may be useful to confirm the diagnosis.
m.s.a.007@hotmail.comMohammed Alkhaibari, Optom open access 2017, 2:2 (Suppl)
DOI: 10.4172/2476-2075-C1-006