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May 01-02, 2017 Toronto, Canada

2

nd

International Conference on

Restorative Dentistry and Prosthodontics

Volume 5, Issue 1 (Suppl)

J Oral Hyg Health

ISSN: 2332-0702 JOHH, an open access journal

Restorative Dentistry & Prosthodontics 2017

May 01-02, 2017

J Oral Hyg Health 2017, 5:1 (Suppl)

http://dx.doi.org/10.4172/2332-0702-C1-006

Periodontitis and cancer: Does a link exist?

Kishan M Sheth

King’s College London Dental School, UK

T

he purpose of this presentation is to carefully analyse the research findings to date regarding a potential link between periodontitis

and carcinogenesis; to evaluate, critically review and explore the variety of potential study confounders and study criteria

differences which suppress the accuracy and validity of the relationship claims being made; gain an appreciation of the biological

plausibility of mechanisms which could be underpinning the relationship between the two diseases; and finally to conclude whether

the current level, findings and quality of research is accurate in supporting the existence of the periodontitis-cancer link. The author

will assess the potential link between periodontitis and several cancerous tumour types, and analyse the evidence regarding the

biological plausibility for the potential association between periodontitis and cancer. The strongest association is present between

periodontitis and oral cancer since each of the three studies looked into show a statistical link between both diseases. The international

burden of cancer has risen every year, a trend that has been paralleled by the increase in periodontitis cases. Research undertaken by

GLOBOCAN (2012), states there were 7.6 million global cancer cases in 2008, and in 2012 there were 14.1 million global cancer cases,

an increase of 84%. Although there is a lack of recent statistical data related to periodontitis cases, between the years 1997 and 2005,

there was an increase of 27% of adults aged between 35 and 44 who had periodontal pocket depths greater or equal to 4 millimeters.

kishan.sheth@kcl.ac.uk