surgery-and-ENT-2016_scientifictracks-abstracts

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Volume 6, Issue 6(Suppl) Surgery Curr Res
ISSN: 2161-1076, an open access journal
Page 32
Notes:
Surgery & ENT 2016
November 07-08, 2016
conferenceseries.com
Surgery & ENT November 07-08, 2016 Alicante, Spain
5th International Conference and Exhibition on
Evaluation of the possible neurotoxic effect of the bone cement on the facial nerve
M Tayyar Kalcioglu1, Numan Kokten1, Oguz Kadir Egilmez2, Mustafa Baran1 and A Isin Dogan Ekici3
1Istanbul Medeniyet University, Turkey
2Malkara State Hospital, Turkey
3Yeditepe University, Turkey
Objective: The aim of that experimental study was to investigate the possible neurotoxic effects of the bone cement (BC) on the facial
nerve with the electrophysiological and histological examinations.
Materials & Methods: Twenty male Wistar albino rats; divided into 4 groups were used in the study. Group A was determined as a
control group and the group B as a sham. In group C; one drop BC was dropped on facial nerve trunk and washed with saline after
waiting 5 seconds. In group D; one drop BC was dropped on facial nerve trunk and the wound was closed primarily after waiting 5
minutes to set BC. Electromyographic measurements (EMG) were performed preoperatively and postoperatively at the fourth week.
Animals were euthanized after applying EMG at the fourth week, facial nerve tissue and environmental samples were taken for the
histopathological examination.
Results: When the EMG wave parameters evaluated in four groups, there was a statistically significant decrease of the postoperative
amplitude levels compared with preoperative amplitude levels in Group D (p<0.05, p=0,014). There was no significant difference
between the groups in terms of inflammation in histopathological evaluation. Foreign body reaction or granulation tissue was not
detected in none of the groups.
Conclusion: To the best of our knowledge, that is the first experimental study which investigates the possible neurotoxic effects of the
BC on the facial nerve with the electrophysiological and histological examinations. Any facial nerve paralysis or nerve conduction
block was not detected in animals by EMG. Opinion of the authors is to show special care to avoid the direct neural contact with BC
in the middle ear surgery, if the contact occurs removal of BC would be beneficial by aspiration and washing with saline.
Biography
M Tayyar Kalcioglu has graduated from Medical faculty of Hacettepe University and worked as an ENT Resident in Inonu University, Department of Otorhinolaryngology,
Turkey. He became an Associate Professor and Professor in Inonu University and has been working in Istanbul Medeniyet University since 2012. He has published more
than 25 papers in reputed journals and has been serving as an Editorial Board Member of repute.
M Tayyar Kalcioglu et al., Surgery Curr Res 2016, 6:6(Suppl)