clinical-trials-2017-scientifictracks-abstracts

16 / 46

Page 49
Notes:
conferenceseries.com
Volume 7, Issue 5 (Suppl) J Clin Trials, an open access journal
ISSN:2167-0870 Clinical Trials 2017
September 11-13, 2017
September 11-13, 2017 San Antonio, USA
4th International Conference on
Cl inical Tr ial s
Dexamethasone as a ropivacaine adjuvant for ultrasound-guided interscalene brachial plexus
block: A randomized, double-blinded clinical trial
Thiago Mamoru Sakae
University of Southern Santa Catarina, Brazil
Objective: The purpose of this study was to evaluate the effect of intravenous or perineural dexamethasone added to ropivacaine
on the duration of ultrasound-guided interscalene brachial plexus blocks (BPB).
Methods: Randomized Clinical Trial. Setting, Patients and Interventions: Sixty ASA physical status I−II patients with
elective shoulder arthroscopic surgeries under interscalene brachial plexus blocks were randomly allocated to receive 20
ml of 0.75% ropivacaine with 1 ml of isotonic saline (C group, n=20), 20 ml of 0.75% ropivacaine with 1 ml (4 mg) of
perineural dexamethasone (Dpn group, n=20), or 20 ml of 0.75% ropivacaine with 1 ml of isotonic saline and intravenous 4
mg dexamethasone (IV) (Div group, n=20). A nerve stimulation technique with ultrasound was used in all patients.
Measurements: The onset time and duration of sensory blocks were assessed. Secondary outcomes were pain scores (VAS) and
postoperative vomiting and nausea (PONV).
Results: The duration of the motor and sensory block was extended in group Dpn compared with group Div and group C
(P<0.05). In addition, within 24 h, group Dpn presented lower levels of VAS and lower incidence of PONV as compared with
the other groups. Moreover, there was a significant reduction on onset time between group Dpn and the other groups.
Conclusions: Perineural 4 mg dexamethasone was more effective than intravenous in extending the duration of ropivacaine in
ultrasound-guided interscalene BPB. Moreover, Dpn has significant effects on onset time, PONV, and VAS.
Biography
Thiago Mamoru Sakae has completed his PhD from Federal University of Santa Catarina, South Brazil and Post-doctoral studies from University of Southern Santa
Catarina – UNISUL, Brazil. He is the Anesthesiologist and Epidemiology Professor at UNISUL, an University in Southern Brazil. He has published more than 130
papers in reputed journals and has been serving as an Editorial Board Member of repute.
Thiago Mamoru Sakae, J Clin Trials 2017, 7:5 (Suppl)
DOI: 10.4172/2167-0870-C1-019