dementia-2016_scientifictracks-abstracts

22 / 46

Notes:
Page 46
Dementia 2016
September 29-October 01, 2016
Volume 6 Issue 5(Suppl) J Alzheimers Dis Parkinsonism 2016
ISSN:2161-0460 JADP, an open access journal
conferenceseries .com
September 29-October 01, 2016 London, UK
5th International Conference on
Alzheimer’s Disease & Dementia
Oleksandr Makarenko et al., J Alzheimers Dis Parkinsonism 2016, 6:5(Suppl)
Recovery and immunological properties of “Cerebral” under the acute stroke
Oleksandr Makarenko1, O Makarenko1, I Vasilieva2 and P Petrov3
1Taras Shevchenko National University of Kyiv, Ukraine
2Institute of Neurosurgery, Ukraine
3Institute of Food Resources, Ukraine
The aim of this work was to study the influence of “Cerebral” on the animal’s conditions after experimental stroke and
on the humoral and cell parts of immunity. We administrated “Cerebral” intraperitoneally to 26 adult guinea pigs with
experimental model of hemorrhage stroke twice with the interval of 6 days. Also, the work was conducted on 30 white mice
for the study of immune reaction. On the 14th – 16th days since the administration of “Cerebral” to guinea pigs considerable
improvement in the state of animals was noted: limb movement recovered, disorders of coordinatation disappeared, tissue
trophism and weight normalized. The animals perform motor and coordinator tests confidently. Establishment of possible
immunotoxical peculiarities an obligate for any new potential medical medicine. “Cerebral” changes the development of
thymus-dependent antigen reaction and hypersensibility of slow tape (SST) reaction, but doesn’t impact on the process of
antibody formation (according to levels of hemolysins and hemoglutinins). “Cerebral” doesn’t have negative influence on the
revealed immunity indexes.
Biography
Makarenko O.M has taken PhD degree at the age of 30 at the Moscow Medical Stomatological Institute, M.D. degree at the age of 40 at the Institute of Higher
Nervous Activity in Moscow. He carries out his post-doc researches at the Institute of higher nervous activity and Taras Shevchenko National University of Kyiv. He
is a professor of the psychology department, the author of more than 200 articles in reputed journals and 5 monographs.