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Volume 6 Journal of Oral Hygiene & Health Oral Health Meet 2018
November 29-30, 2018
Page 39
Notes:
conferenceseries.com
November 29-30, 2018 Bali, Indonesia
International Conference on
Oral Health and Dental Medicine
Oral Submucous Fibrosis (OSMF): Is aflatoxin B1 & iron responsible? Haridra (turmeric) ayurvedic
remedy
Rahul R Bhowate
Datta Meghe Institute of Medical Sciences (Deemed to be University), India
Statement of the Problem: Chewing betel nut with or without tobacco is widespread in Indian continent. In Rural area habit of
betel nut chewing with or without tobacco started at an early age and is available as a commercial product or prepared manually
by pan vendors at affordable cost. Prevalence of oral submucous fibrosis (OSMF) is increasing and leading to an epidemic of
oral pre-malignant condition followed by development of oral malignancy in Indian population. Various studies have reported
the presence of Aflatoxin B 1 in betel nut (Raisuddin S et al) and also it's hepatotoxic, mutagenic & carcinogenic effect. It has
been suggested by various authors that it has severe effects on the liver function, as it causes disruption in the protein synthesis.
Aflatoxin is also responsible for defects in RBC cell wall, making it more susceptible for haemolysis. The purpose of this study
is to evaluate Serum aflatoxin B1 antibody, Iron & MDA level & formulate herbal treatment protocol for OSMF. Methodology:
Purposive samples of OSMF were included in the study population for estimation of serum aflatoxin B1 antibody; Iron &MDA
Level & these sufferers were treated with whole extract of Haridra (Turmeric).
Findings: Serum aflatoxin, iron & MDA levels were increased in OSMF compared with healthy controls. Treatment with
Haridra extract showed significant improvement in OSMF cases.
Conclusion & Significance: Understanding of etiopathogenesis, epidemiology with clinical presentation and evidence based
support from molecular and cellular pathway of disease Haridra is the favorable Ayurvedic remedy for the treatment of OSMF
& prevention of malignant transformation.
Biography
Rahul R Bhowate BDS, MDS & MPhil is Professor in Oral Medicine & Radiology & Convener, Dental Education Unit at Datta Meghe Institute of Medical Sciences,
Sharad Pawar Dental College & Hospital, Sawangi Meghe, Wardha, Maharashtra, India. Dr. Bhowate did his Dental schooling and post-graduation in Oral Medicine
& radiology at Govt. Dental College & Hospital, Nagpur, India. He is working in the field of Preventive Oral Oncology. He is member of several prestigious national
and international organizations and he is reviewer of several leading journals.
Rahul R Bhowate, J Oral Hyg Health 2018, Volume 6
DOI: 10.4172/2332-0702-C2-011