Conference on Genetic Syndromes & Gene Therapy 2012
International Conference on
Genetic Syndromes & Gene Therapy
November 19-21, 2012 Hilton San Antonio Airport, USA
Gene Therapy-2012

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    Organizing Committee Members


     
    Waclaw Szybalski
    Professor Emeritus
    Department of Oncology
    School of Medicine and Public Health
    University of Wisconsin-Madison
    USA
    Tel:(608) 262-1259
     
    		  
    Biography :
    Prof Waclaw Szybalski is the Father of Gene Therapy. With his team, they were the first ever, who transformed the human cells with the externally engineered transgenes (Szybalska, E.H., Szybalski, W., 1962. Genetics of human cell lines. IV. DNA mediated heritable transformation of a biochemical trait. Proc. Natl. Acad. Sci. 48, 2026-2034). This work created the foundations for what is now called gene therapy. Therefore, this year, we celebrate the 50th Anniversary of this ground breaking work. He earned his Doctoral Degree at the University of Gdansk. Poland, EU. He is currently a professor of Oncology at the McArdle Laboratory for Cancer. He the author of 232 peer-reviewed articles on the subject.    BIOGRAPHY
    Research Interest :
    Novel methods for genome mapping and sequencing     RESEARCH INTEREST
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    Publications
     
    Kenneth Blum
    Professor
    Department of Psychiatry
    University of Florida
    USA
    Tel: 619- 890-2167
    Fax: 352-273-8342
     
    		  
    Biography :
    Kenneth Blum is currently Chairman of the Board and Chief Scientific Officer of LifeGen, Inc. San Diego, California and managing partner of Reward Deficiency Solutions, LLC, and San Diego, California. He was formerly Full Professor of Pharmacology, University of Texas, at San Antonio, Texas for 23 years (retired). He is currently Full Professor of the Department of Psychiatry and McKnight Brain Institute University of Florida College of Medicine, Gainesville Florida. He served as Research Professor in the Department of Physiology and Pharmacology, Wake forest College of Medicine, Winston-Salem, North Carolina. He serves as scientific Director, PATH Foundation, NY, New York. He has received numerous awards including NIDA Career Teacher Award; American Chemical Society Speakers Award; Gordon Conference Research Award; Presidential Excellence award (National Council of Alcoholism and Drug Abuse). Dr Blum has authored and edited eleven books, was an editor –in –chief of an Elsevier Journal, and has published over 400 peer reviewed papers. Coined “Brain Reward Cascade and Reward Deficiency Syndrome RDS) and is credited as the lead author in the first association of the Dopamine D2 receptor gene with severe alcoholism (JAMA, 1990). He is considered by many as the father of Psychiatric Genetics.” and Neuroadaptagen Amino-Acid Therapy (NAAT). Dr. Blum holds both US & foreign patents on Nutrigenomics. He serves on 7 editorial boards and is the associate editor on two boards including section editor of Integrative Omics and Applied Biotechnology journal and is an ad hock reviewer for 40 journals world-wide.    BIOGRAPHY
    Research Interest :
    Psychopharmacology, Neuropharmacology, Genetics, Psychiatric Genetics, Pharamcogenomics,Nutrigenomics nutrition omics    RESEARCH INTEREST
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    Publications
     
    Roland W. Herzog
    Professor
    Department of Pediatrics
    Microbiology and Molecular Genetics
    University of Florida
    USA
    Tel: 352-273-8113
    Fax: 352-273-8342
     
    		  
    Biography :
    Roland W. Herzog, Ph.D. is Associate Professor of Pediatrics, Molecular Genetics and Microbiology at the University of Florida, Gainesville, FL. He is member of the Division of Molecular and Cellular Therapy, the UF Genetics Institute, Shands Cancer and Powell Gene Therapy Centers. After completing a PhD in Microbiology (Auburn University, 1992-1996) and postdoctoral training (Children’s Hospital of Philadelphia 1996-2000), Dr. Herzog became faculty member at the University of Pennsylvania School of Medicine (Philadelphia, PA), before joining UF in 2005. He received, among other awards, a Career Development Award from the National Hemophilia Foundation, an Outstanding New Investigator Award from the American Society of Gene and Cell Therapy, and a Bayer Hemophilia Award. Dr. Herzog serves on the editorial boards of the journals Current Gene Therapy, Gene Therapy, and Human Gene Therapy, and he is a Deputy Editor of the journal Molecular Therapy. He has served as reviewer for several other leading biomedical journals, the National Institutes of Health, and several other funding agencies. Dr. Herzog has published two books and more than 80 articles and has received multiple federal grants for his research program. He has given numerous invited lectures at national and international meetings.    BIOGRAPHY
    Research Interest :
    Gene therapy for hemophilia, Adeno-associated viral (AAV) vectors, Liver-directed gene therapy, Immune responses to coagulation factors, Organ-specific immunity, Immune     RESEARCH INTEREST
    Network
    Publications
     
    Kenneth Lundstrom
    CEO
    Pan Therapeutics
    Switzerland
    Tel: 41-79-776-6351
     
    		  
    Biography :
    Dr. Kenneth Lundstrom has a broad expertise in gene expression, viral vectors and gene therapy. He received his Ph.D. in molecular genetics from the University of Helsinki, Finland and conducted post-doctoral research at Cetus Corporation in California. Dr. Lundstrom was appointed Senior Scientist at Orion Pharmaceuticals and was involved in studies on Catechol-o-methyltransferases. From 1992-95 he developed Semliki Forest Virus Vectors for Overexpression of Membrane Proteins at the Glaxo Institute of Molecular Biology, in Geneva, Switzerland. Dr. Lundstrom worked as Principal Biologist at the Glaxo Medicines Research Centre in Stevenage, UK 1995-96. From 1996-2001 he was responsible for Receptor Expression in the CNS Department at Roche, in Basel, Switzerland. Dr. Lundstrom was in 2001 appointed the Scientific Coordinator of the MePNet program, a Structural Genomics Program on GPCRs. He also joined the Senior Management Team of Regulon Inc, Mountain View, California, a cancer therapy company. In 2006 Dr. Lundstrom was appointed Director of Research, VP at Flamel Technologies in Lyon, France. In 2009 Dr. Lundstrom established PanTherapeutics in Lausanne, Switzerland a cancer gene therapy applying viral vectors. Dr. Lundstrom has published more than 150 research and review articles in international journals.    BIOGRAPHY
    Research Interest :
    gene expression, viral vectors, gene therapy, structural biology, drug dicovery, drug delivery    RESEARCH INTEREST
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    Publications
     
    Marek Malecki
    Associate Professor
    Department of Genetics, Genomics, and Gene Therapy
    Western University of Health Sciences
    USA
    Tel: 909-706-3547
     
    		  
    Biography :
    Marek Malecki MD PhD is currently an Associate Professor of Genetics, Genomics, and Gene Therapy at the Western University of Health Sciences, Pomona, CA. He acquired his expertise in molecular medicine during the fellowships at the Rigshospitalet, Copenhagen, Denmark and in molecular biology and genetics during the EMBO, Heidelberg, Germany funded postdoctoral fellowships. He is the author of the cancer suicide therapy. He is the inventor of the synthetic molecules facilitating genomic nanosurgery.    BIOGRAPHY
    Research Interest :
    Cancer    RESEARCH INTEREST
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    Publications
     
    Ancha Baranova
    Associate Professor
    Department of Molecular and Microbiology
    George Mason University
    USA
    Tel: 571-334-11-45
     
    		  
    Biography :
    Ancha Baranova, a specialist in the area of functional genomics of complex human diseases, is an Associate Professor in the School of Systems Biology, College of Science, George Mason University in Fairfax, Virginia, USA. Baranova\\\'s major academic contributions are in the field of functional genomics, with emphasis on cancer and metabolic syndrome-related disorders. A significant part of Baranova’s efforts is dedicated to in silico analysis of the publicly available genomics and proteomics databases. Baranova directs a team of postgraduate and graduate associates that employs a multidisciplinary approach in order to broaden research perspective in the genetics of complex human diseases. Baranova has published about 50 manuscripts in international journals including Genomics, Hepatology, Clinical Cancer Research, FASEB Journal, FEBS Letter, Bioinformatics, Leukemia and Lymphoma, Oncogene, and others.     BIOGRAPHY
    Research Interest :
    functional genomics of complex human diseases    RESEARCH INTEREST
    Network
    Publications
     
    Jack M. Sullivan
    Associate Professor
    Ophthalmology, Physiology & Biophysics Pharmacology & Toxicology, and Neuroscience and the Ira G. Ross Eye Institute
    Staff Physician-Scientist, Veterans Administration Western NY Healthcare System
    University at Buffalo- SUNY
    USA
    Tel: 716-862-6533
    Fax: 716-862-6824
     
    		  
    Biography :
    BIOGRAPHY
    Research Interest :
    Retina; Gene therapy; Neurodegenerative disorders; Pathophysiology; Protein Folding; Gene Expression; Signal Transduction    RESEARCH INTEREST
    Network
    Publications
     
    Iraida Sharina
    Assistant Professor
    Department of Internal Medicine
    University of Texas Medical School
    USA
    Tel: 713-486-2480
     
    		  
    Biography :
    Research program of Dr. Sharina′s laboratory is focusing on the studies of diverse genetic processes that regulate the expression and function of major Nitric Oxide (NO) receptor soluble guanylyl cyclase (sGC). NO is a crucially important signaling molecule in physiology of diverse organisms. NO initiate a number of signaling cascades, of which arguably the most significant is the activation of sGC which generates the ubiquitous secondary messenger cGMP. sGC is the only known NO-inducible guanylyl cyclase and provides a unique link transducing increases in NO concentrations to activation of various downstream effector enzymes such as cGMP-binding protein kinases, phosphodiesterases and cyclic nucleotide gated ion channels. The sGC activity is crucial for a number of physiological functions including regulation of smooth muscle relaxation in vascular and gastric tissues, inhibition of platelet aggregation andadhesion,neurotransmission and neuromodulation. The sGC activity is an important therapeutic target for organic nitrates in treatment of various cardiovascular disorders. However, genetic mechanisms participating in regulation of sGC expression still remain a mystery. Dr. Sharina′s laboratory actively investigates how the expression of sGC genes is regulated on transcriptional and post-transcriptional levels in different cell types and physiological conditions including embryonic development and stress response. The group especially interested in determining the role of splicing in modulation of the diversity and abundance of sGC transcripts.    BIOGRAPHY
    Research Interest :
    Research program of Dr. Sharina′s laboratory is focusing on the studies of diverse genetic processes that regulate the expression and function of major Nitric Oxide (NO)     RESEARCH INTEREST
    Network
    Publications
     
    Brittney-Shea Herbert
    Associate Professor
    Department of Medical & Molecular Genetics
    Indiana University School of Medicine
    USA
    Tel: 317-278-6147
    Fax: 317-274-1069
     
    		  
    Biography :
    BIOGRAPHY
    Research Interest :
    genetic mechanisms of breast cancer, developing and testing novel therapies or preventative strategies that can target telomerase    RESEARCH INTEREST
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    Publications
     
    Girish V. Shah
    Professor & Chair of Pharmacology
    School of Pharmacy
    University of Louisiana
    USA
    Tel. 318-342-1693
    Fax: 318-342-1737
     
    		  
    Biography :
    Dr.Girish V. Shah completed Ph.D. in Biochemistry from University of Bombay, 1979
    Post-Doctoral Training: Karolinska Institute, Stockholm
    Max Planck Research unit for Reproductive Medicine
    McMaster University, Canada
    Academic Appointments: Instructor: University of Tennessee Health Sciences Center-Memphis (1986-90)
    Associate Professor: University of Kansas Medical Center (1990-98)
    Professor: Texas Tech University of Health Sciences Center (1998-2003)
    Endowed Chair: University of Louisiana (2003-to date)     BIOGRAPHY
    Research Interest :
    Our research focuses on: 1) Identifying factors that promote progression of localized prostate cancer to its metastatic form, and identifying means of blocking this process; and 2) Identifying and validating early biomarkers for detection of prostate cancer. Our research encompasses the study of a gene function at cellular and molecular level, and development of in vivo models for tumor growth and metastasis including athymic nude and transgenic mouse models. We have strong expertise in the area drug discovery, drug pharmacology, cancer therapy, evaluation of cancer biomarkers, and pre-clinical testing of new drug candidates    RESEARCH INTEREST
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    Publications
     
    Prem Arora
    Paediatrics Advisory Member
    Wayne State University
    Children’s Hospital of Michigan
    USA
    Tel: 313-745-4000
     
    		  
    Biography :
    Graduated from medical school in India (Maulana Azad Medical College) in 2002. Residency training in India (Maulana Azad Medical College) and in United states (Wayne State University School of Medicine, Detroit Medical Center).Fellowship in neonatal-perinatal medicine (Wayne State University School of Medicine, Children Hospital of Michigan). Was elected as fellow of the American Academy of Pediatrics in 2011. Has published articles in peer reviewed journals in fields of pediatrics, neonatology and nutrition.    BIOGRAPHY
    Research Interest :
    Endothelial progenitor cell profile across different gestational ages, pulse wave velocity and augmentation index in premature and term infants, neonatal transport.    RESEARCH INTEREST
    Network
    Publications
     
    Yiqiang Cai
    Associate Professor
    Department of Internal Medicine
    Yale University School of Medicine
    USA
    Tel: 203-737-2941
     
    		  
    Biography :
    Cai graduated from Hunan Medical University in China (M.D. equivalent) and from the Tokushima University School of Medicine in Japan (Ph.D.). Dr. Cai currently is the research faculty member of Section of Nephrology at Yale University School of Medicine and Yale PKD Center, and is also the Guest (Visiting) Professor of Central South University, South Medical University, and Chen-Du Medical College of China. Dr. Cai is the co-author in more than 40 research publications in well recognized journals including “Science”, “Cell”, “Nature Genetics”, “Nature Cell Biology”, “J Biol Chem” etc., Dr. Cai is the four times recipient of the Travel Award of the American Society of Nephrology (05’, 08’, 09’, and 10’), and the recipient of the American Heart Association Scientist Development Award, the PKD Foundation Research Grant, the NIH Sponsored Nephrology Training Grant , and the Fujii-Ostuka Fellowship for International Exchange Program (Japan). Dr. Cai had been invited to give lectures in Universities in USA, Canada, South Korea and China, and invited to serve as the reviewer for the \"Journal of American Society of Nehrology\", \"Kidney International\", \"Cancer Letter\", and “African Journal of Biotechnology”. Dr. Cai also serves as the editorial board member for the “World Journal of Nephrology” and for the journal “Health”.    BIOGRAPHY
    Research Interest :
    Dr. Cai’s primary research interest is on the study of polycystic kidney disease with current focus on the molecular basis of the PKD pathogenesis.    RESEARCH INTEREST
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    Publications
     
    Juan Ren
    Professor
    Cancer Center
    Xian Jiao tong University
    China
    Tel: 86-29-8266-7777
     
    		  
    Biography :
    BIOGRAPHY
    Research Interest :
    1. Mechanisms of Tumor angiogenesis 2. Mechanisms of Tumor metastasis 3. Roles and functions study of lysophospholipids and their receptors    RESEARCH INTEREST
    Network
    Publications
     
    Martin Ehler
    German Research Center for Environmental Health
    Institute of Biomathematics and Biometry
    Germany
    Phone: 49-89-3187-2393
    Fax: 49-89-3187-3369
     
    		  
    Biography :
    Martin Ehler came 2008 to the National Institutes of Health after receiving his PhD at the University of Marburg/Germany in mathematics and computer science. As the only mathematician in the Section on Medical Biophysics at NIH, he is committed to interdisciplinary research and has published in mathematical as well as biomedical journals. He uses harmonic analysis together with modern tools in statistics in order to study retinal development and related fields. Since 2011, the NIH and the German Science Foundation support his own project on Sparsity and Dimension Reduction in Biomedical Data Analysis at the Helmholtz Zentrum Mynchen, German Research Center for Environmental Health.    BIOGRAPHY
    Research Interest :
    Retinal development and related fields    RESEARCH INTEREST
    Network
    Publications
     
    Jianzhong Su
    Professor
    College of Bioinformatics Science and Technology
    Harbin Medical University
    China
    Tel. 86-0451-8665-0721
    Fax: 86-0451-8336-6235
     
    		  
    Biography :
    BIOGRAPHY
    Research Interest :
    i) storage and analysis of high-throughput DNA methylation and histone modification data by the statistics and combination methods. ii) investigation of epigenetic regulatory mechanisms of DNA methylation and histone modifications in cellular differentiation and cancerogenesis by the methods of system bioloby such as network analysis. iii)evolution of epigenetic modification elements in eukaryotes    RESEARCH INTEREST
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    Publications
    Genetic Conference, Symposium, Genetics Conferences
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