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Volume 9

Chemical Sciences Journal

Asia Chemistry 2018

September 12-13, 2018

Annual Congress on

September 12-13, 2018 Singapore

Chemistry

Terpenes, Coumarins, Steroids, Flavonoids and Flavonoid Glycosides from species

Pulicaria

and their

biological activity

K A Eshbakova

Acad.

. Yunusov Institute of the Chemistry of Plant Substances Academy of Sciences of the Republic of Uzbekistan, Uzbekistan

edicinal plants are an important component of plant communities. Their study has a significant scientific and practical

importance, related to the conservation of their resources and their sustainable use. Plant of the family Asteraceae are

widespread in nature and are rich sources of flavonoids, terpenoids and coumarin in the flora of Uzbekistan. Flavonoids, terpenoids

and coumarins the class of natural compounds, which are characterized by structural diversity, and versatile high activity and low

toxicity. From the plant family Asteraceae isolated natural compounds with cytotoxic, antioxidant, hypoglycemic, lipid-lowering,

hepatoprotective, antibacterial and other types of activity. In Uzbekistan there are more than 596 species of plants from the

family Asteraceae. Of these, only a few species studied. Therefore, the study of phenolic compounds and terpenoid plant family

Asteraceae

actually represents a certain theoretical interest, are of great scientific and fundamental. Learning new structure of

flavonoids, coumarins and terpenoids will make some contribution to the chemistry of natural compounds, and will help address

the problems associated with Chemotaxonomy and finding new physiologically active compounds. Plants of the species Pulicaria

belong to family of Asteraceae, widely distributed in the flora Uzbekistan and used in the folk medicine. Study their chemical

components and identify biological activity of current interest. We have studied four representatives of the species

Pulicaria:

Pulicaria salviifolia, Pulicaria gnaphalodes

and

Pulicaria uliginosa

. Aerial parts these plants we have isolated a new and known

compounds in relation to terpenoids, coumarins, flavonoids, sterols, phenols and studied their biological activity. The isolated

compounds showed highly hypoglycemic, hypolipidemic, vitiligo, anti-cancer, hinotropic, antihypertensive, anticoagulants and

spasmolytic effects.

Chem Sci J 2018, Volume 9

DOI: 10.4172/2150-3494-C5-030