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Euro Biotechnology 2016
November 07-09, 2016
Volume 6, Issue 7(Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
conferenceseries .com
November 07-09, 2016 Alicante, Spain
12th Euro Biotechnology Congress
Plant biomolecules in health: Effect on skin healing
Fazouane-Naimi Fethia and Ait-Aourahoun Karima
University of Boumerdes, Algeria
Medicinal plants growing in Algeria feature pharmacological properties distinguished according to their adaptation to the
climates of different regions and during the seasons. The aimof our work is to search in the plant biodiversity representing
a local genetic resource, the plants traditionally used and to identify which biomolecules have a healing effect on burns and
wounds. These are Phlomiscrinita, Carthamuscaeruleus and Pistacialentiscus. These plants are genetically different but have
common phytochemical characteristics such as the presence of abundant molecules in plant organs (leaves, rhizomes, fruits)
such as polyphenols, O-glycosides, C-glycosides, mucilage, the saponins and unsaturated fatty acids. GPC analysis revealed
that Pistacialentiscus is rich in oleic acid (14.94%), linolenic acid (36.17%), linoleic acid (28.90%); Phlomiscrinita is rich in oleic
acid (18.33%), linoleic acid (39.83%); Carthamuscaeruleus is rich in oleic acid (12.94%) and myristic acid (70.03%). The second
phase of our study is the ointment formulation based on plant extracts from aqueous macerated from Phlomiscrinita, rhizomes
for Carthamuscaeruleus and oil seeds of Pistacialentiscus for wound rats which suffered from surface burns and wounds. The
wound assessment is made by macroscopic observations, planimetric studies, statistical and histological studies. The ointment
showed a positive effect on wound healing with a significant contraction reaching approximately on the fourth day with 50%
shrinkage and to achieve 100% reduction on fourteenth day against 96% for the wounds treated with Madécassol. The plant
extract ointment showed an obvious healing activity consistent with the efficacy which is used in folk medicine. These plants
can be phylogenetic in perspective study and can be used in the production of recombinant enzymes involved in the synthesis
of their biomolecules.
Fazouane-Naimi Fethia et al., J Biotechnol Biomater 2016, 6:7(Suppl)