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Volume 8 Journal of Gastrointestinal & Digestive System Gastro Meet 2018
August 06-07, 2018
August 06-07, 2018 Abu Dhabi, UAE
Gastroenterology and Digestive
Disorders
16th International Conference on
Helicibacter infection among dyspeptic and non-dyspeptic HIV patient at Yeka Health Center: Case
control study
Getachew Seid
Ethiopia
Background: Helicobacter pylori are a potent engenderer of urease. HIV infected patients experience many forms of opportunistic
infections, including gastrointestinal symptoms. The exact role of H. pylori infection among HIV infected patients in causing
gastrointestinal symptoms such as dyspepsia remains obscure. There are circumscribed data regarding H. pylori infection in HIV
positive patients in cognation to CD4 count in our region and country. There for we aimed to assess the prevalence of H. pylori
infection utilizing stool antigen among dyspeptic and non-dyspeptic HIV patients and its cognation with CD4 T cell count.
Methods: A case control study enrolling 370 study participants was conducted from January- June 2017. Socio-demographic
and clinical data were amassed and 3 milliliter blood was drawn aseptically for the CD4+T cell count and complete blood count.
Stool samples were accumulated for H. pylori stool antigen test. Data ingression and analysis was done utilizing SPSS version
20.confidence level of 95%was used statistical significance.
Results: A total of 185 cases and 185 controls were participated in the study. H. pylori antigen was detected in 117 (31.62%) of the
total participants. The prevalence of H. pylori infection of cases and control was 60/185 (32.43%) and 57/185 (30.81%), respectively
(AOR=1.097, 95%CI: 0.689-1.747, p=0.697). Inboth case and control groups, no significant associationwas observed in the prevalence of H.
pylori with age, family size, educational status,marital status, toilet use habit, occupation, alcohol drinking, cigarette smoking andkhat chewing
(p>0.05). In both case and control group H. pylori infection was higher in patients with CD4 T cell count greater than 200 cells/μl.
Conclusion: The prevalence of H. pylori infection was slightly higher among cases than control patients. The infection was not
significantly associated with social, demographic and behavioral factors while it was higher in patients with higher CD4 T cell
count. The observed prevalence of H. pylori stool antigen positivity necessitates the need to diagnose it in patients with higher
CD4 T cell count and thus minimize the clinical consequences of infection.
J Gastrointest Dig Syst 2018, Volume 8
DOI: 10.4172/2161-069X-C3-071