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Volume 7, Issue 5 (Suppl) Otolaryngol
ISSN: 2161-119X Otolaryngol, an open access journal Otolaryngology 2017
October 18-19, 2017
October 18-19, 2017 Dubai, UAE
4th International Conference on
Rhinology and Otology
A Langerhans cell histiocytosis in its rare Letterer-Siwe form in a child mimicking osteoarthritis: A
case report and literature review
Bouali Mustapha, H Mezhoud, H Soltani and I Fergoug
Oran University Hospital, Algeria
Langerhans cell histiocytosis (LCH) is a group of three rare diseases (annual incidence less than 4/1000.000H) with increasing
aggressiveness respectively: Eosinophilic granuloma (unifocal solitary osteolytic lesion), Hand-Schuller-Christian disease
(multifocal lesion) and Letterer-Siwe disease (themost aggressive, disseminated disease with systemicmanifestations). e bone
is most commonly involved with a predilection for the skull. Some cases of temporal bone localizations have been described
in the literature. We report a case of an 18-month child presenting a LCH of the temporal bone misdiagnosed at the beginning
as osteoarthritis. In fact, the child presented a retro-auricular swelling with in ammatory characters, fever and otorrhea. e
exploration before surgery revealed besides the extensive temporal lesion, hematologic perturbations, a splenomegaly and
a hepatomegaly. e histopathology con rmed the diagnosis of a LCH. We describe the diagnosis challenges, the surgical
di culties and the therapeutic response of the child.
Otolaryngol 2017, 7:5 (Suppl)
DOI: 10.4172/2161-119X-C1-023