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Volume 7, Issue 6(Suppl) J Chromatogr Sep Tech
ISSN: 2157-7064 JCGST, an open access journal
Page 37
Notes:
Separation Techniques 2016
September 26-28, 2016
conferenceseries.com
Separation Techniques
September 26-28, 2016 Valencia, Spain
2nd International Conference and Expo on
Separation science that’s built for biopharma
Robert Van Ling
Thermo Fisher Scientific, Netherlands
Biopharmaceuticals now dominate the leading positions in both sales and revenue tables over traditional small molecule
drugs and drug pipelines continue to lead by biopharmaceuticals. In addition, as some of the earlier biopharmaceuticals
begin to come off patent, we are seeing tremendous growth and attention in biosimilars. Both biopharmaceuticals and
biosimilars however present new challenges compared to small molecules due to their complexity and variability; and as such
manufacturers need advanced analytical tools to be able to effectively characterize these biopharmaceuticals to ensure efficacy
and safety of the product. In this seminar, I will overview the latest advances made by Thermo Fisher Scientific with respect
to UHPLC instrumentation and column chemistries for complete biopharmaceutical separation and characterization. The
Thermo Scientific™ Vanquish™ Flex UHPLC system is truly built for biopharma offering precise and reproducible separations,
coupled with flexibility to execute all major biopharmaceutical applications. Our extensive portfolio of column chemistries
combines with the Vanquish Flex to offer a complete solution for biopharmaceutical analysis. Examples of characterizing
monoclonal antibodies to determine amino acid sequence, charge variants, aggregates, purity and glycan profiles will be
presented.
Biography
Robert Van Ling has started working at LC Packings, focusing on Nano and Capillary LC. Following the successful introductions of UltiMate, the world’s first Nano
LC system, LC Packings was acquired by Dionex Corp., in which he has held several roles in conveying the use of Nano LC-MS in Proteomics, for both ESI and
MALDI applications and later moving more towards separation of intact proteins and Protein Therapeutics. Since 2012, he has been working as a Member of the
Thermo Fisher Scientific family. Currently, he is supporting wide portfolio of chromatography consumables and specifically sample preparation and characterization
of large molecules and biologics.
Robert Van Ling, J Chromatogr Sep Tech 2016, 7:6(Suppl)