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Journal of Pharmaceutical care and Health Systems | ISSN: 2376-0419 | Volume 5
Pharmaceutical sciences
11
th
World Congress on
September 28-29, 2018 | Montreal, Canada
Antifungal activity of
Stachys acerosa
Boiss extract on Candida species isolated fromOral Candidiasis
Nasrin Amirrajab, Sadegh Tehrani, Yusef Yalaly, Ehsan Ahmadi, Sedigheh Yusef Naanaie
and
Batool Sadeghi-Nejad
Ahvaz Jundishapur University of Medical Sciences, Iran
Background and Purpose:
Dental caries is one of the most important global health problems. Yeasts, including Candida
species, are also found in the oral cavity as a normal flora. An alternative approach to overcoming these issues may be the use
of natural and phytochemical antimicrobials. The Middle East is exclusively used for medicinal plants used to treat diseases and
infections in traditional medicine for thousands of years (1-3). On the other hand, the most of these synthetic antimicrobial
products have some adverse effects, which make them less popular. Hence, the aim of this study was to evaluate the antifungal
properties of
Stachys acerosa
extracts against Candia species.
Materials and Methods:
In this study, we assessed the activities of
Stachys acerosa
leaf extracts against Candida species,
including
C. albicans, C. glabrata, C. tropicalis
, using the agar-well diffusion method.
Results:
The minimal inhibitory concentrations (MICs) values of fruit and leaf extracts from Stachys acerosa leaf extracts
ranged 3.12-12.5 mg/ml against the tested Candida.
Conclusion:
Based on the results, the ethanolic extracts of the selected plants exhibited antifungal potency against the tested
fungi and could be used as an alternative natural antifungal agent and recommended to be used in the formulation of herbal
mouthwash and toothpaste in future researches.
Biography
Nasrin Amirrajab Members of Scientist Academic (Assistant professor, PhD Medical Mycology) of Department of Laboratory Sciences, School of Paramedicine /
Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Nasrin Amirrajab et al., J Pharma Care Health Sys 2018, Volume 5
DOI: 10.4172/2376-0419-C3-033