Acne is, affecting over 80% of teenagers (aged 13–18 years) at some point. Estimates of prevalence vary depending on study populations and the method of assessment used. Prevalence of acne in a community sample of 14–16 year olds has been recorded as 50% and it has been estimated that up to 30% of teenagers have acne of sufficient severity to require medical treatment.
There is some low-quality evidence from single trials that LGLD, tea tree oil, and bee venom may reduce total skin lesions in acne vulgaris, but there is a lack of evidence from the current review to support the use of other CAMs, such as herbal medicine, acupuncture, or wet-cupping therapy, for the treatment of this condition.
People may also be affected before and after puberty. Though it becomes less common in adulthood than in adolescence, nearly half of people in their twenties and thirties continue to have acne. About 4% continue to have difficulties into their forties.