The tumors that develop from pituitary glands are referred to as Pitutary tumors. 90% of the pituitary tumors diagnosed are adenomas. Multiple oncogene abnormalities may be involved in this type of tumorigenesis. The mutations involved can be ras gene mutations, G-protein abnormalities, p53 gene deletions, mutations, and rearrangements etc.
A new oncogene, pituitary tumor transforming gene-1 that serves as marker for endocrine malignancies have been discovered. This gene is over expressed in case of Pitutary Tumors.All Pituitary tumors are not cancerous. 1 out of 4 people may have a pituitary adenoma without knowing it. The estimated cases of Pituitary Tumors in Norway are 665.
Treatment of Pitutary tumors mainly depends on type of the tumor, size of the tumor, and how deep it has grown into the brain. Generally, used treatment methods for Pitutary tumours are surgery, radiation therapy and medications, either alone or in combination and also to bring back the production of hormones to normal levels.