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Membranous Nephropathy

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  • Membranous nephropathy

    Membranous nephropathy (MGN) is one of the more common forms of nephrotic syndrome in the adult population. It can be idiopathic or secondary (30%). The two can be distinguished by clinical, laboratory, and histological features.

  • Membranous nephropathy

    Disease pathophysiology: 

    Although the exact mechanisms causing pMN are still under investigation, different studies show a strong relationship betweenantibody levels to podocytic proteins and disease activity. Membranous nephropathy is quite rare among the general population but is one of the more common glomerular diseases.

  • Membranous nephropathy

    Disease statistics:

    Idiopathic membranous nephropathy (MN) is one common cause of idiopathic nephrotic syndrome in adults; 25% of MN patients proceed to end-stage renal disease. In adults, membranous nephropathy is a lead cause of nephrotic syndrome, with about 75% of the cases idiopathic.

     

  • Membranous nephropathy

    Disease treatment: 

    Treatment of membranous nephropathy focuses on addressing the cause of your disease and relieving your symptoms. There is no certain cure. In cases where membranous nephropathy is caused by a medication or another disease — such as acancerous tumor — stopping the medication or controlling the other disease usually improves the condition.

  • Membranous nephropathy

    Major research on disease:

    Immunosuppressive Treatment for Nephrotic Idiopathic Membranous Nephropathy: A Meta-Analysis Based on Chinese Adults.  Nephrotic syndrome is a relatively rare but important manifestation of kidney disease.

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