Aortic valve disease is usually a condition in which the valve between the main pumping chambers of heart (left ventricle) and the main artery to body (aorta) shows abnormalities in their work. Aortic valve disease sometimes a condition which may be present at the time of birth (congenital heart disease), or it may result from other causes.
Histopathologic investigations of aortic sclerosis show central subendothelial plaquelike sores on the aortic side of the handout that stretch out to the nearby fibrosa layer. Likenesses to atherosclerosis are available in these injuries, with conspicuous amassing of "atherogenic" lipoproteins, including LDL and lipoprotein(a), proof of LDL oxidation, a provocative cell invade, and minute calcification
Statistics The prevalence in the Brazil of any valve disease is 2.0%. Of those with valve disease about 0.4% have aortic stenosis. The prevalence of moderate or severe aortic stenosis in patients more than 75 years old is 3.8%. It is the most common valvular heart disease of the elderly and increases with age. The prevalence is 3.0% at age 75 years and 6.1% at 85 years