Transposition of the great vessels is a heart defect that occurs from birth (congenital). The two major vessels that carry blood away from the heart -- the aorta and the pulmonary artery -- are switched (transposed). A baby with transposed arteries is cyanotic - the medical term for bluish discoloration of the skin because of deficient oxygenation of the blood - shortly after birth.
The blueness doesn't go away even if the baby is given extra oxygen. For a baby with transposed arteries to survive, blood flow between the right and left sides of the heart must be increased. P CHDs affect nearly 149,392?births per year in the Canada. Research is going on Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada.