Lymphoma is cancer that begins in cells of the lymph system. The lymph system is part of the immune system, which helps the body fight infection and disease. Because lymph tissue is found all through the body, lymphoma can begin almost anywhere. The two main types of lymphoma are Hodgkin lymphoma and non-Hodgkin lymphoma (NHL). In non-Hodgkin's lymphoma, tumors develop from lymphocytes — a type of white blood cell. Non-Hodgkin's lymphoma is more common than Hodgkin lymphoma. Approximately 2.9 percent of men and women will be diagnosed with non-Hodgkin lymphoma every year. About 800 cases are being registered each year. Relative frequency Crude incidence rate is 11.2
Many new chemotherapy drugs are being studied in clinical trials. In recent years, these studies have led to the approval of drugs such as bendamustine (Treanda) and pralatrexate (Folotyn) for use against certain types of lymphoma. Other studies are looking at new ways to combine drugs using different doses or different sequences of drugs. Intermediate- and high-grade lymphomas may result in the following examination findings:
• Skin lesions: Associated with cutaneous T-cell lymphoma (mycosis fungoides), anaplastic large-cell lymphoma, and angioimmunoblastic lymphoma.