Definition: Small vessel disease is a condition in which the small arteries in the heart become narrowed. Small vessel disease causes signs and symptoms of heart disease, such as chest pain (angina). Small vessel disease is sometimes called coronary microvascular disease or small vessel heart disease. It's usually diagnosed after a doctor checks for blockages in the main arteries of the heart but finds little or no narrowing in the large vessels, even though your symptoms persist.
Symptoms: Chest pain, squeezing or discomfort, Chest pain associated with discomfort in your left arm or jaw, Chest pain that worsens with daily activities and at times of emotional stress, Neck, shoulder, upper back or abdominal discomfort, Shortness of breath, Unusual fatigue, A loss of energy, Trouble sleeping.
Statistics: Among age- and gender-matched subjects, confluent WMH were significantly more prevalent in Chinese (38·5%) than Whites (28·4%; P = 0·01). There was no difference in the prevalence of lacunes (Chinese 29·1% vs. Whites 29·5%, P = 0·93) and microbleeds (Chinese 10·1% vs. 9·0%, P = 0·67) between Chinese and Whites. In multivariable logistic regression, Chinese ethnicity was associated with confluent WMH (odds ratio 1·7, 95% confidence interval 1·1-2·6, P = 0·01), but no differences were seen for lacunes and microbleeds. The association between Chinese ethnicity with confluent WMH became insignificant when subjects with history of stroke were excluded.