Bleeding disorders are a group of disorders that share the inability to form a proper blood clot. Improper clotting can be caused by defects in blood components such as platelets and/or clotting proteins, also called clotting factors. Symptoms of a bleeding disorder include: Bleeding into joints, muscles and soft tissues, Excessive bruising, Prolonged, heavy menstrual periods (menorrhagia). Approximately 10,000 deaths were attributed to blood diseases in 2010. These include the following: 4,900 due to anemia’s, 1900 due to coagulation defects, 800 due to purpura, 2400 due to other blood diseases. In India, the incidence of haemophilia is nearly 1 in 5000 males.
This condition is more common in males as compared to females. It has been postulated that in our country around 1300 children are born with haemophilia every year. Complete blood count (CBC): to check the amount of blood loss as well as the amount of red and white blood cells you have), platelet aggregation test, bleeding time: to see how fast your blood vessels close to prevent bleeding. Treatment for bleeding disorders varies, depending on the condition and its severity. For some bleeding disorders, there are clotting factor concentrates that can be infused prophylactically or on-demand at home, to prevent or treat bleeds
Many of today's standards of research are based upon what was learned from clinical trials in the past such as reducing complications of clots, what causes clots. Some bleeding disorders, such as hemophilia, can be inherited or acquired. Others can occur from such conditions as anemia, cirrhosis of the liver, HIV, leukemia and vitamin K deficiency, lot of research is being done on these topics.