Non-allergic rhinitis is characterized by sporadic or persistent perennial nasal symptoms that do not result from IgE-mediated immunopathologic events.The symptoms of allergic rhinitis result from exposure to allergens in a susceptible (sensitized) individual. Allergens include pollen, grass, weed, and house-dust mite etc., and symptoms are triggered by the interaction of an allergen with immunoglobulin E (IgE) molecules which bind through the high affinity IgE receptor to the surface of mast cells in the nasal mucosa or to circulating basophils. Recognition of the allergen by the IgE antibody leads to activation of the mast cell or basophil, causing the release of a variety of mediators, including histamine and leukotrienes, which in turn attract inflammatory cells from the peripheral circulation. This orchestrated chain of events results in the characteristic clinical features of allergic rhinitis.
Allergic rhinitis is one of the most common conditions in Ireland. Studies estimate that more than 30% of people experience the condition at some point in their life.It may also trigger asthma attacks in susceptible individuals — 90 per cent of people with asthma will also have allergic rhinitis and 30 per cent of people with allergic rhinitis will have asthma as well. More allergy symptoms are seen in Ireland, which has one of the world’s highest rates of asthma. In order to understand treatment, it is helpful to visit the poison ivy analogy.With skin exposure to poison ivy, there's a few things a patient can do to minimize or avoid symptoms altogether-Wash the skin immediately, Avoid areas with poison ivy, Wear protective clothing, Medications.