High cholesterol (hypercholesterolemia) can be inherited, but it's often the result of unhealthy lifestyle choices, and thus preventable and treatable. A healthy diet, regular exercise and sometimes medication can go a long way toward reducing high cholesterol.
High cholesterol typically doesn't cause any symptoms. In the vast majority of cases, the only true symptoms it may cause are emergency events. For instance, a heart attack or stroke can result from the damage caused by high cholesterol over time. These events typically don’t occur until high cholesterol leads to the formation of plaque in your arteries.
A review of existing data from randomized controlled trials confirms that solid evidence on optimal BP and LDL-C targets is missing, possible interactions between BP and LDL-C lowering treatments have never been directly investigated, and evidence in favour of a beneficial effect of BP or LDL-C lowering on cognitive decline is, at best, very weak.