It is an acute often fatal, form of haemorrhagic fever. It is caused by a filovirus ( Marburg virus ) which normally lives in African monkeys. It is a severe illness of humans and non-human primates caused by either of the two marburgviruses, Marburg virus (MARV) and Ravn virus (RAVV). MVD is a viral hemorrhagic fever(VHR).
Symptoms: It may include: Nausea and vomiting. Diarrhea (may be bloody) Red eyes. Raised rash. Chest pain and cough. Stomach pain. Severe weight loss. Bleeding, usually from the eyes, and bruising (people near death may bleed from other orifices, such as ears, nose and rectum).
Diagnosis: Marburg virus infections can be diagnosed definitively only in laboratories, by a number of different tests: enzyme-linked immunosorbent assay (ELISA); antigen detection tests; serum neutralization test; reverse-transcriptase polymerase chain reaction (RT-PCR) assay; and. virus isolation by cell culture.
Treament: Treatment is primarily supportive in nature and includes minimizing invasive procedures, balancing fluids and electrolytes to counter dehydration, administration of anticoagulants early in infection to prevent or control disseminated intravascular coagulation, administration of procoagulants late in infection to control hemorrhaging, maintaining oxygen levels, pain management, and administration of antibiotics or antimycotics to treat secondary infections.
Epidemology: The outbreak involved 25 primary MARV infections and seven deaths, and six nonlethal secondary cases.