alexa Pagets disease of Bone | Italy| PDF | PPT| Case Reports | Symptoms | Treatment

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Pagets Disease Of Bone

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  • Pagets disease of Bone

    Paget's disease of bone is an incessant issue that can bring about extended and distorted bones. Paget's is created by the extreme breakdown and development of bone, trailed by disrupted bone rebuilding. This reasons influenced issue that remains to be worked out, bringing about agony, distorted bones, breaks and joint inflammation in the joints close to the influenced bones. Osteosarcoma is a rare complication of Paget's disease with a very poor prognosis. 

  • Pagets disease of Bone

    The infection is more normal in more established individuals and those of Northern European plunge. Men are more probable than ladies to have the ailment. Paget's disease of bone is an incessant issue that can bring about extended and distorted bones. Paget's is created by the extreme breakdown and development of bone, trailed by disrupted bone rebuilding.This reasons influenced issue that remains to be worked out, bringing about agony, distorted bones, breaks and joint inflammation in the joints close to the influenced bones.

  • Pagets disease of Bone

    Treatment is controversial: the older age of the patients affected by Paget's disease may limit the use of chemotherapy and axial involvement may limit the practicality of surgery. We retrospectively reviewed the medical records of 26 patients treated between 1961 and 2006 who had bone sarcoma arising from a site of Paget's disease. Twenty two of the 26 patients had surgery. In six surgery only was performed; three had surgery, adjuvant chemotherapy, and radiotherapy; one surgery and radiotherapy; 12 underwent surgery and chemotherapy, adjuvant in 10 patients and neoadjuvant in two; two had only radiotherapy and two had only chemotherapy. We performed survival analyses between various combinations of treatment. Despite improvements in surgery and medical treatments the prognosis remains poor in patients with Paget's sarcoma. Around one million individuals in the Italy have Paget's malady.

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