Pathophysiology: Viral hemorrhagic fever (VHFs) is a general term to severe group of illness caused by RNA viruses from several viral families. It is a severe multisystem syndrome caused by infectious viruses which lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal and gastrointestinal (GI) bleeding.VHF is caused by viruses of four families: arenaviruses, filoviruses, bunyaviruses, and flaviviruses.
Disease Statistics: In 2014 a study was published according to which one species, Reston ebola virus, has been reported outside Africa, in the Philippines and China. This virus does not seem to affect humans, although some people may seroconvert. However, it can cause fatal illness in some species of nonhuman primates. Between 1989 and 1996, Reston ebola virus was isolated repeatedly at primate quarantine facilities in the U.S. and Italy.
Treatment: Patients usually receive supportive therapy but as such there are no other treatment or established cure for VHFs. Ribavirin, an anti-viral drug, have been effective in treating some individuals with Lassa fever or HFRS. Treatment with convalescent-phase plasma has been used with success in some patients with Argentine hemorrhagic fever.
Research: Researchers of Iowa State University College of Veterinary Medicine conducted this study.