Adenoviruses are very common and come in many types. Depending on the virus type, adenoviruses can cause respiratory (breathing) problems that can include cough, fever, and runny nose, headache, sore throat and eye infections. Infection with adenovirus can also rarely lead to more serious problems, such as pneumonia, stomach and bowel problems, and even death. Some people who are infected may have to be hospitalized. Adenovirus infection can be spread from person to person through the air (for example, by sneezing or coughing).
Adenovirus vaccine contains live adenovirus Type 4 and Type 7. It will prevent most illness caused by these two virus types. Adenovirus vaccine comes as two tablets, taken orally (by mouth) at the same time. The tablets should be swallowed whole, not chewed or crushed. Adenovirus vaccine may be given at the same time as other vaccines.
Approximately 25, 000 reports to WHO from 1967 to 1976 on isolations of adenovirus 1 to 31 showed an absolute frequency of Ad2, 1, 7, 3, 5, 6, 4, 8, and other species, in decreasing order. The relative frequency was analyzed by the X2 method; only significant deviations (p < 0.05; in many cases p < 0.001) from chance distribution were taken into account. To avoid small numbers, the three adenovirus species of subgenus A (Ad12, 18, 31) and several species of subgenera B and D were analyzed as one group.