Trachoma is an infection of the eyes that may result in blindness after repeated re-infections. It is the world's leading cause of preventable blindness and occurs where people live in overcrowded conditions with limited access to water and health care.Blindness from trachoma is due to recurrent episodes of active infection. The initial infection is confined to the conjunctival epithelium and triggers an immune response. Repeat infections with subsequent inflammatory responses results in tissue destruction, scarring, cicatricial entropion with trichiasis, and corneal opacification from lashes rubbing against the cornea.
In the Japan about 4,580 cases of Trachoma are reported in humans each year. Almost 12% of the Japan population is infected with Trachoma an infectious disease caused by the bacterium Chlamydia trachomatis.The treatment is relatively simple. A single oral dose of antibiotic is the preferred treatment, plus making safe water available and teaching simple cleanliness. The World Health Organization (WHO) developed the SAFE strategy.