Barrett’s esophagus is also called columnar epithelium lined lower oesophagus (CELLO). It is caused due to abnormal changes occur within the cell of the lower portion of the esophagus. The main reason for Barrett,s esophagus is chronic acid exposure from reflex esophagus. Mostly this kind of condition found in 5-10% patients who diagnosed for gastroesophageal reflux disease (GERD). Although, many of the patients with barrett’s esophagus do not have symptoms.
Symptoms: Barrett’s esophagus does not cause any particular symptoms, however it is associated with below mentioned symptoms. • heartburn • dysphagia • hematemesis • pain under the sternum where the esophagus meets the stomach • unintentional weight loss because eating is painful
Treatment: For barrett’s esophagus doctors will approach different types of treatment that is depend up on the severity of disease those includes medicines, Endoscopic ablative therapies, Endoscopic mucosal resection, Surgery. Doctors prefer acid supressing medicine like proton pump inhibitor; an Endoscopic ablative therapy is performing by using different methods those are Photodynamic therapy, Radiofrequency ablation; In endoscopic mucosal resection, your doctor lifts the Barrett’s tissue, injects a solution underneath or applies suction to the tissue, and then cuts the tissue off. The doctor then removes the tissue with an endoscope; many of the doctors prefer surgery because this is having very less complications.
Among 2107 individuals with Barrett’s esophagus, 79 underwent esophagectomy and 80 underwent endoscopic ablation. The mean age was 63.1 10.6 years in the surgical group and 69.79.4 years in the ablation group (P<.0001). Among high-grade dysplasia/intramucosal carcinoma patients, 9 of 76 (12%) first seen by a gastroenterologist underwent esophagectomy, whereas 18 of 21 (86%) first seen by a surgeon underwent esophagectomy. In a logistic regression model, factors associated independently with esophagectomy were as follows: patient age of 60 or younger (odds ratio [OR], 4.95; 95% confidence interval [CI], 1.65–14.9), cancer stage T1sm or greater (OR, 16.0; 95% CI, 5.60 – 45.6), and initial consultation performed by a surgeon (vs gastroenterologist) (OR, 35.1; 95% CI, 9.58 –129)