Deep vein thrombosis, or deep venous thrombosis, (DVT) is the formation of a blood clot (thrombus) within a deep vein, predominantly in the legs. Non-specific signs may include pain, swelling, redness, warmness, and engorged superficial veins. DVT often develops in the calf veins and "grows" in the direction of venous flow, towards the heart. When DVT does not grow; it can be cleared naturally and dissolved into the blood (fibrinolysis).
We conducted a multicentric cross-sectional survey that included medical and surgical patients from 43 hospitals throughout Mexico. Patients who were at risk for DVT according to the ACCP 2004 guidelines were included and evaluated for thromboprophylaxis. Overall, 625 patients were at risk: 308 (49%) surgical patients and 317 (51%) medical patients. There were 179 (58%) surgical patients receiving recommended prophylaxis, whereas medical patients represented 117 (37%) patients.
The basic treatments for the disease are Anticoagulation, which prevents further coagulation, home treatment, stockings, walking, and repeat imaging and IVC filters, thrombolysis, and thrombectomy. The aims of the physicians are to prevent clot becoming larger, clot becoming lose and traveling to lungs, new clot formation and Post thrombotic syndrome.
Major Research on Disease
The current major research on the diseases are efficacy of low doses of heparin for the prevention of the DVT after a major surgery, accuracy of the clinical assessment for DVT, Decreased plasma levels of activated factor VII in patients with deep vein thrombosis etc