Definition: Any type of depression can make you feel sad and keep you from enjoying life. However, atypical depression — also called depression with atypical features — means that your depressed mood can brighten in response to positive events. Other key symptoms include increased appetite, sleeping too much, feeling that your arms or legs are heavy, and feeling rejected.
Symptoms: Depression that temporarily lifts in response to good news or positive events, Increased appetite that can cause weight gain, Increased desire to sleep, usually more than 10 hours a day, Heavy, leaden feeling in your arms or legs that lasts an hour or more in a day — a feeling that is different from fatigue, Sensitivity to rejection or criticism, which affects your relationships, social life or job.
Statistics: Compared to others, atypical responders (6.8%) showed different symptom profiles, with higher 'mood reactivity' and 'suicidal ideation' and lower levels of mild symptoms like 'sad mood'. Atypical responding was associated with more medication use (especially tricyclic antidepressants: OR=1.5), less somatization (OR=0.8), anxiety severity (OR=0.8) and anxiety diagnoses (OR=0.8-0.9), and was shown relatively stable (29.0%) over time.