Generally 30% to 40% of patients with occupational nickel allergy develop hand eczema. Involvement of the hands in a nickel-sensitized patient should raise the possibility that nickel is acting as an occupational allergen. A dermatologist also can do a simple skin patch test. The doctor puts tiny amounts of nickel and other allergens on patches, which are applied to your upper back. If your skin is cracked or blistered, you should take off any metal jewelry right away and see your doctor for treatment to prevent infection.
Once you develop a sensitivity to nickel, you will develop a rash (contact dermatitis) whenever you come into contact with the metal. medications to reduce irritation and improve the condition of a rash from a nickel allergy reaction are: Corticosteroid cream, Nonsteroidal creams, Oral corticosteroid, Oral antihistamine. But nickel can be found in many everyday items — from coins to zippers, from cellphones to eyeglass frames. Once you develop nickel allergy, however, you will always be sensitive to the metal and need to avoid contact.