Takayasu arteritis is a rare, systemic, most commonly affects women of childbearing age. It is a inflammatory large-vessel vasculitis disease involving inflammation in the walls of the largest arteries in the body: the aorta and its main branches. The disease results from an attack by the body's own immune system, causing inflammation in the walls of arteries.
Predominantly Caucasian population studied from Netherlands, Germany and England, where Takayasu's arteritis is rare, had a higher frequency of A allele as compared to our controls. . Fifty-two patients underwent at least 1 surgical procedure. The main indications for intervention were renal vascular hypertension, cerebral hypoperfusion, and limb claudication.
Particularly these patients needing immunosuppressive drugs. Glucocorticoids (prednisone, prednisolone or others), often referred to as “steroids,” are an important part of treatment. The dose and length of treatment depend on how bad the disease is and how long the patient has had it. Lasting damage to arteries sometimes needs a vascular procedure or surgical treatment.