Sclerosing mesenteritis is an uncommon idiopathic disorder characterised by chronic non-specific inflammation involving the adipose tissue of the bowel mesentery. sclerosing mesenteritis is asymptomatic, gastrointestinal symptoms such as abdominal pain, nausea/vomiting, bloating, loss of appetite, weight loss and diarrhea or constipation, Occasionally, intermittent partial bowel obstruction is encountered. Non-gastrointestinal symptoms include fatigue, weight loss, night sweats and fever.
Tests and procedures used to diagnose sclerosing mesenteritis include. 1. Physical exam: sclerosing mesenteritis often forms a mass in upper abdomen that can be felt during a physical exam. 2. Imaging tests: Imaging tests of your abdomen may reveal sclerosing mesenteritis. Imaging tests may include computerized tomography or magnetic resonance imaging. 3. Biopsy: Removing a sample of tissue for testing.
Glucocorticoid drugs such as prednisone, which relieve inflammation. They may be used in combination with azathioprine and colchicine.Hormonal therapy such as tamoxifen has also been shown to work. Sometimes hormonal therapy is used together with glucocorticoid drugs.Several other medications such as azathioprine, colchicine, Cyclophosphamide and thalidomide.