Antiphospholipid syndrome occurs when immune system mistakenly attacks some of the normal proteins in r blood. Antiphospholipid syndrome can cause blood clots to form within arteries or veins. Antiphospholipid syndrome may cause blood clots to form in leg veins, a condition known as deep vein thrombosis (DVT).
Signs and symptoms of antiphospholipid syndrome may include: Blood clots in legs (deep vein thrombosis, or DVT) that may travel to lungs (pulmonary embolism), Repeated miscarriages or stillbirths and other complications of pregnancy, such as premature delivery and high blood pressure during pregnancy (preeclampsia), Stroke, Blood clots in the arteries of arms or legs (peripheral arterial thrombosis).
Blood tests for antiphospholipid syndrome look for at least one of the following three antibodies in blood: Lupus anticoagulant, Anti-cardiolipin, Beta-2 glycoprotein I. Doctors generally use medications that reduce blood's tendency to clot to treat antiphospholipid syndrome. This doesn't cure the disease but does help to prevent its most serious complications.