Pediatric Thrombocytopenia is a condition in which you have a low blood platelet count. Platelets (thrombocytes) are colorless blood cells that help blood clot. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries. Thrombocytopenia often occurs as a result of a separate disorder, such as leukemia or an immune system problem. Or it can be a side effect of taking certain medications. It affects both children and adults. Thrombocytopenia may be mild and cause few signs or symptoms. In rare cases, the number of platelets may be so low that dangerous internal bleeding occurs. Treatment options are available.
Major bleeding occurred in 6.9% of the 398 patients treated with bivalirudin and 9.0% of the 404 patients treated with heparin. Despite the trend, the difference in risk between the two treatments was not statistically significant (relative risk [RR] 0.77; 95% CI 0.48–1.23). Other measures of bleeding, including severe, life-threatening, or major bleeding, showed no advantage of bivalirudin.
Specific treatments for thrombocytopenia will be determined by your child’s physicians based on the cause and severity of the disease, as well as your child’s tolerance for medications, procedures and therapies. Mild cases may not require treatment and may resolve on their own. Blood transfusions with platelets or red blood cells are sometimes needed.
The clinical consequences of iron deficiency anemia include preterm delivery, perinatal mortality, and postpartum depression. Fetal and neonatal consequences include low birth weight and poor mental and psychomotor performance.