Sclerosing mesenteritis is a rare condition of unknown cause that is characterized by chronic mesenteric inflammation . The process usually involves the mesentery of the small bowel, especially at its root, but can occasionally involve the mesocolon. sclerosing mesenteritis is asymptomatic, gastrointestinal symptoms such as abdominal pain, nausea/vomiting, bloating, loss of appetite, weight loss and diarrhea or constipation, Occasionally, intermittent partial bowel obstruction is encountered. Non-gastrointestinal symptoms include fatigue, weight loss, night sweats and fever.
Includes abdominal surgery or trauma , autoimmunity , paraneoplastic syndrome, ischaemic injury and infection.small bowel mesentery is affected in most cases although the sigmoid mesocolon and omentum can also be occasionally be involved.Sclerosing mesenteritis is itself non-neoplastic, but it is often associated with an underlying malignancy.
Sclerosing mesenteritis is a rare benign condition that is found most often in elderly patients. Various terms are used throughout the literature to describe this condition, which may lead to confusion, especially since there is a paucity of data regarding this rare disease.The disease includes three stages.Stage-1: mesenteric lipodystrophy, degeneration of mesenteric fat.Stage-2: mesenteric panniculitis, inflammatory reaction. Stage-3: retractile mesenteritis / sclerosing mesenteritis, fibrosis, which may be associated with distortion or lymphatic obstruction.