Genetic Association Information Network

The Genetic Association Information Network (GAIN) is an open private organization of the Foundation for the National Institutes of Health, Inc. (FNIH) and incorporates associations with the National Institutes of Health (NIH) and the private division.

Pick up backings a progression of Genome-Wide Association Studies (GWAS) intended to recognize particular purposes of DNA variety connected with the event of a specific regular malady. Specialists from existing case-control or trio (guardian posterity) studies were welcome to submit tests and information on about 2,000 members for test of 300,000 to 500,000 single nucleotide polymorphisms intended to catch approximately 80 percent of the regular variety in the human genome. Particular qualities required in ailment procedures can be distinguished once specific territories of the genome are connected with ailment event.

With the sequencing of the human genome, lower expense and more proficient advances, and the investigation of basic examples of hereditary variety through the International Haplotype Map (Hap Map) venture, we now have the strategies and instruments important to reveal causal qualities that add to malady helplessness, and in this manner encourage disclosure of new atomic focuses for aversion, conclusion and treatment.

Applications for access to GAIN genotyping were submitted on May 9, 2006 and ventures chose for genotyping were declared at the American Society of Human Genetics yearly meeting on October 10, 2006. They incorporate studies on Attention Deficit Hyperactivity Disorder (ADHD), bipolar turmoil, diabetic nephropathy, significant depressive issue, psoriasis and schizophrenia. The subsequent information has been kept into the database of Genotype and Phenotype (dbGaP) inside the National Library of Medicine at the NIH for the wide utilization of the examination group