Lymphoma means a cancer of the lymphatic system. There are 2 main types of lymphoma: Hodgkin lymphoma and Non Hodgkin lymphoma (NHL).. In non-Hodgkin's lymphoma, tumors develop from lymphocytes — a type of white blood cell. Non-Hodgkin's lymphoma is more common than Hodgkin lymphoma. In Sweden, Denmark, and Finland, the NHL incidence increased in both genders and all age categories by about 4% every year up until the early 1990s. Thereafter, the incidence increased at a slower rate (ages 60-79 years), stabilized (ages 50-59 and > or =80 years), and decreased (ages 0-49 years), respectively, similarly for males and females in the three countries. Time trends of NHL were not reciprocated and explained by trends for other lymphoproliferative malignancies nor explained by trends in NHL as secondary primaries or NHL diagnosed postmortem.
A study is looking at a new type of scan called magnetic resonance spectroscopy (MRS) to see if it can help to predict which type of treatment will work best for individual patients. MRS gives information about the activity inside a cancer, by looking at chemical changes. Researchers want to collect information from the scans and create a database so that they can see how patients' individual biological differences affect how well particular treatments work for them. Laboratory studies in a patient with suspected NHL should include the following:
•CBC count: May be normal in early-stage disease; in more advanced stages, may demonstrate anemia, thrombocytopenia/leukopenia
•Serum chemistry studies: May show elevated LDH and calcium levels, abnormal liver function tests
•Human T-cell lymphotropic virus-1 serology: For patients with adult T-cell leukemia/lymphoma